Publications (2005)

  1. Flemming, D., Stolpe, S., Schneider, D., Hellwig, P., and Friedrich, T. (2005) A Possible Role for Iron-Sulfur Cluster N2 in Proton Translocation by the NADH:Ubiquinone Oxidoreductase (Complex I). J. Mol. Microbiol. Biotechnol. 10:208-222. [PM:16645316].
  2. Boiangiu, C. D., Jayamani, E., Brugel, D., Herrmann, G., Kim, J., Forzi, L., Hedderich, R., Vgenopoulou, I., Pierik, A. J., Steuber, J., and Buckel, W. (2005) Sodium ion pumps and hydrogen production in glutamate fermenting anaerobic bacteria. J. Mol. Microbiol. Biotechnol. 10:105-119. [PM:16645308].
  3. Hedderich, R. and Forzi, L. (2005) Energy-Converting [NiFe] Hydrogenases: More than Just H2 Activation. J. Mol. Microbiol. Biotechnol. 10:92-104. [PM:16645307].
  4. Perier, C., Tieu, K., Guegan, C., Caspersen, C., Jackson-Lewis, V., Carelli, V., Martinuzzi, A., Hirano, M., Przedborski, S., and Vila, M. (2005) Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage. Proc. Natl. Acad. Sci. U. S. A 102:19126-19131. [PM:16365298].
  5. Hielscher, R., Wenz, T., Stolpe, S., Hunte, C., Friedrich, T., and Hellwig, P. (2005) Monitoring redox dependent contribution of lipids in FTIR difference spectra of complex I from E. coli. Biopolymers [PM:16358245].
  6. Grad, L. I., Sayles, L. C., and Lemire, B. D. (2005) Introduction of an additional pathway for lactate oxidation in the treatment of lactic acidosis and mitochondrial dysfunction in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A 102:18367-18372. [PM:16344465].
  7. Gonzalo, R., Garcia-Arumi, E., Llige, D., Marti, R., Solano, A., Montoya, J., Arenas, J., and Andreu, A. L. (2005) Free radicals-mediated damage in transmitochondrial cells harboring the T14487C mutation in the ND6 gene of mtDNA. FEBS Lett. 579:6909-6913. [PM:16337195].
  8. Yun, N. R., San, K. Y., and Bennett, G. N. (2005) Enhancement of lactate and succinate formation in adhE or pta-ackA mutants of NADH dehydrogenase-deficient Escherichia coli. J. Appl. Microbiol. 99:1404-1412. [PM:16313413].
  9. Abdrakhmanova, A., Dobrynin, K., Zwicker, K., Kerscher, S., and Brandt, U. (2005) Functional sulfurtransferase is associated with mitochondrial complex I from Yarrowia lipolytica, but is not required for assembly of its iron-sulfur clusters. FEBS Lett. 579:6781-6785. [PM:16310785].
  10. Brito, J. A., Bandeiras, T. M., Teixeira, M., Vonrhein, C., and Archer, M. (2005) Crystallisation and preliminary structure determination of a NADH: quinone oxidoreductase from the extremophile Acidianus ambivalens. Biochim. Biophys. Acta [PM:16303338].
  11. Lee, S. J., Youn, Y. C., Han, E. S., and Lee, C. S. (2005) Depressant effect of mitochondrial respiratory complex inhibitors on proteasome inhibitor-induced mitochondrial dysfunction and cell death in PC12 cells. Neurochem. Res. 30:1191-1200. [PM:16292513].
  12. Drose, S., Galkin, A., and Brandt, U. (2005) Proton pumping by complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica reconstituted into proteoliposomes. Biochim. Biophys. Acta 1710:87-95. [PM:16289468].
  13. Joza, N., Oudit, G. Y., Brown, D., Benit, P., Kassiri, Z., Vahsen, N., Benoit, L., Patel, M. M., Nowikovsky, K., Vassault, A., Backx, P. H., Wada, T., Kroemer, G., Rustin, P., and Penninger, J. M. (2005) Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy. Mol. Cell Biol. 25:10261-10272. [PM:16287843].
  14. Abe, M., Murai, M., Ichimaru, N., Kenmochi, A., Yoshida, T., Kubo, A., Kimura, Y., Moroda, A., Makabe, H., Nishioka, T., and Miyoshi, H. (2005) Dynamic Function of the Alkyl Spacer of Acetogenins in Their Inhibitory Action with Mitochondrial Complex I (NADH-Ubiquinone Oxidoreductase). Biochemistry 44:14898-14906. [PM:16274237].
  15. Sirvent, P., Bordenave, S., Vermaelen, M., Roels, B., Vassort, G., Mercier, J., Raynaud, E., and Lacampagne, A. (2005) Simvastatin induces impairment in skeletal muscle while heart is protected. Biochem. Biophys. Res. Commun. 338:1426-1434. [PM:16271704].
  16. Piruat, J. I. and Lopez-Barneo, J. (2005) Oxygen tension regulates mitochondrial DNA-encoded complex I gene expression. J. Biol. Chem. 280:42676-42684. [PM:16257962].
  17. Bao, L., Avshalumov, M. V., and Rice, M. E. (2005) Partial mitochondrial inhibition causes striatal dopamine release suppression and medium spiny neuron depolarization via H2O2 elevation, not ATP depletion. J. Neurosci. 25:10029-10040. [PM:16251452].
  18. Panov, A., Dikalov, S., Shalbueva, N., Taylor, G., Sherer, T., and Greenamyre, J. T. (2005) Rotenone model of Parkinson's disease: Multiple brain mitochondria dysfunctions after short-term systemic rotenone intoxication. J. Biol. Chem. 280:42026-42035. [PM:16243845].
  19. Mayorov, V., Biousse, V., Newman, N. J., and Brown, M. D. (2005) The role of the ND5 gene in LHON: Characterization of a new, heteroplasmic LHON mutation. Ann. Neurol. 58:807-811. [PM:16240359].
  20. Hoglinger, G. U., Lannuzel, A., Khondiker, M. E., Michel, P. P., Duyckaerts, C., Feger, J., Champy, P., Prigent, A., Medja, F., Lombes, A., Oertel, W. H., Ruberg, M., and Hirsch, E. C. (2005) The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy. J. Neurochem. 95:930-939. [PM:16219024].
  21. Vogel, R. O., Janssen, R. J., Ugalde, C., Grovenstein, M., Huijbens, R. J., Visch, H. J., Van den Heuvel, L. P., Willems, P. H., Zeviani, M., Smeitink, J. A., and Nijtmans, L. G. (2005) Human mitochondrial complex I assembly is mediated by NDUFAF1. FEBS J. 272:5317-5326. [PM:16218961].
  22. Cantin, A., Lopez-Gresa, M. P., Gonzalez, M. C., Moya, P., Miranda, M. A., Primo, J., Romero, V., Peris, E., and Estornell, E. (2005) Novel inhibitors of the mitochondrial respiratory chain: oximes and pyrrolines isolated from Penicillium brevicompactum and synthetic analogues. J. Agric. Food Chem. 53:8296-8301. [PM:16218678].
  23. Visch, H. J., Koopman, W. J., Leusink, A., van Emst-de Vries SE, van den Heuvel, L. W., Willems, P. H., and Smeitink, J. A. (2005) Decreased agonist-stimulated mitochondrial ATP production caused by a pathological reduction in endoplasmic reticulum calcium content in human complex I deficiency. Biochim. Biophys. Acta 1762:115-123. [PM:16213125].
  24. Sato, I., Miyado, M., and Sunohara, M. (2005) NADH dehydrogenase activity and expression of mRNA of complex I (ND1, 51kDa, and 75kDa) in heart mitochondria of klotho mouse. Okajimas Folia Anat. Jpn. 82:49-56. [PM:16212276].
  25. Lee, J., Kim, C. H., Simon, D. K., Aminova, L., Andreyev, A., Kushnareva, Y., Murphy, A. A., Lonze, B. E., Kim, K. S., Ginty, D. D., Ferrante, R. J., Ryu, H., and Ratan, R. R. (2005) Mitochondrial creb mediates mitochondrial gene expression and neuronal survival. J. Biol. Chem. 280:40398-40401. [PM:16207717].
  26. Ogilvie, I., Kennaway, N. G., and Shoubridge, E. A. (2005) A molecular chaperone for mitochondrial complex I assembly is mutated in a progressive encephalopathy. J. Clin. Invest 115:2784-2792. [PM:16200211].
  27. Pearce, L. L., Kanai, A. J., Epperly, M. W., and Peterson, J. (2005) Nitrosative stress results in irreversible inhibition of purified mitochondrial complexes I and III without modification of cofactors. Nitric. Oxide. 13:254-263. [PM:16185902].
  28. Schuh, R. A., Kristian, T., Gupta, R. K., Flaws, J. A., and Fiskum, G. (2005) Methoxychlor Inhibits Brain Mitochondrial Respiration and Increases Hydrogen Peroxide Production and CREB Phosphorylation. Toxicol. Sci. 88:495-504. [PM:16177237].
  29. Abu-Amero, K. K., Bosley, T. M., Bohlega, S., and McLean, D. (2005) Complex I respiratory defect in LHON plus dystonia with no mitochondrial DNA mutation. Br. J. Ophthalmol. 89:1380-1381. [PM:16170145].
  30. Horvath, A., Horakova, E., Dunajcikova, P., Verner, Z., Pravdova, E., Slapetova, I., Cuninkova, L., and Lukes, J. (2005) Downregulation of the nuclear-encoded subunits of the complexes III and IV disrupts their respective complexes but not complex I in procyclic Trypanosoma brucei. Mol. Microbiol. 58:116-130. [PM:16164553].
  31. Forzi, L., Koch, J., Guss, A. M., Radosevich, C. G., Metcalf, W. W., and Hedderich, R. (2005) Assignment of the [4Fe-4S] clusters of Ech hydrogenase from Methanosarcina barkeri to individual subunits via the characterization of site-directed mutants. FEBS J. 272:4741-4753. [PM:16156794].
  32. Zanna, C., Ghelli, A., Porcelli, A. M., Martinuzzi, A., Carelli, V., and Rugolo, M. (2005) Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G. Apoptosis. 10:997-1007. [PM:16151635].
  33. Chen, Y. R., Chen, C. L., Zhang, L., Green-Church, K. B., and Zweier, J. L. (2005) Superoxide generation from mitochondrial NADH dehydrogenase induces self inactivation with specific protein radical formation. J. Biol. Chem. 280:37339-37348. [PM:16150735].
  34. Korenaga, M., Wang, T., Li, Y., Showalter, L. A., Chan, T., Sun, J., and Weinman, S. A. (2005) Hepatitis C virus core protein inhibits mitochondrial electron transport and increases ROS production. J. Biol. Chem. 280:37481-37488. [PM:16150732].
  35. Luft, F. C. (2005) How complex is Complex I? J. Mol. Med. 83:749-751. [PM:16143865].
  36. Hinttala, R., Uusimaa, J., Remes, A. M., Rantala, H., Hassinen, I. E., and Majamaa, K. (2005) Sequence analysis of nuclear genes encoding functionally important complex I subunits in children with encephalomyopathy. J. Mol. Med. 83:786-794. [PM:16142472].
  37. Richardson, J. R., Quan, Y., Sherer, T. B., Greenamyre, J. T., and Miller, G. W. (2005) Paraquat Neurotoxicity is Distinct from that of MPTP and Rotenone. Toxicol. Sci. 88:193-201. [PM:16141438].
  38. Canter, J. A., Kallianpur, A. R., Parl, F. F., and Millikan, R. C. (2005) Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res. 65:8028-8033. [PM:16140977].
  39. Duval, R. A., Poupon, E., Brandt, U., and Hocquemiller, R. (2005) Remarkable substituent effect: beta-aminosquamocin, a potent dual inhibitor of mitochondrial complexes I and III. Biochim. Biophys. Acta 1709:191-194. [PM:16139789].
  40. Su, Z. H., Imura, Y., and Osawa, S. (2005) Evolutionary history of Calosomina ground beetles (Coleoptera, Carabidae, Carabinae) of the world as deduced from sequence comparisons of the mitochondrial ND5 gene. Gene 360:140-150.[PM:16139442].
  41. Cardol, P., Gonzalez-Halphen, D., Reyes-Prieto, A., Baurain, D., Matagne, R. F., Remacle, C. (2005) The mitochondrial oxidative phosphorylation proteome of Chlamydomonas reinhardtii deduced from the Genome Sequencing Project. Plant Physiol. 137:447-459. [PM:15710684].
  42. Fandino, A. S., Rais, I., Vollmer, M., Elgass, H., Schagger, H., and Karas, M. (2005) LC-nanospray-MS/MS analysis of hydrophobic proteins from membrane protein complexes isolated by blue-native electrophoresis. J. Mass Spectrom. 40:1223-1231. [PM:16127664].
  43. Cleren, C., Starkov, A. A., Calingasan, N. Y., Lorenzo, B. J., Chen, J., and Beal, M. F. (2005) Promethazine protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Neurobiol. Dis. 20:701-708. [PM:16126396].
  44. Hirata, Y. and Nagatsu, T. (2005) Rotenone and CCCP inhibit tyrosine hydroxylation in rat striatal tissue slices. Toxicology 216:9-14.[PM:16115719].
  45. Adam-Vizi, V. (2005) Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources. Antioxid. Redox. Signal. 7:1140-1149. [PM:16115017].
  46. Sousa, S. C. and Castilho, R. F. (2005) Protective Effect of Melatonin on Rotenone plus Ca2+-Induced Mitochondrial Oxidative Stress and PC12 Cell Death. Antioxid. Redox. Signal. 7:1110-1116. [PM:16115015].
  47. Cronan, J. E., Fearnley, I. M., and Walker, J. E. (2005) Mammalian mitochondria contain a soluble acyl carrier protein. FEBS Lett. 579:4892-4896. [PM:16109413].
  48. Kotlyar, A. B., Karliner, J. S., and Cecchini, G. (2005) A novel strong competitive inhibitor of complex I. FEBS Lett. 579:4861-4866. [PM:16107251].
  49. Battaglia, V., Salvi, M., and Toninello, A. (2005) Oxidative stress is responsible for mitochondrial permeability transition induction by salicylate in liver mitochondria. J. Biol. Chem. 280:33864-33872.[PM:16100122].
  50. Wasilewski, M. and Wojtczak, L. (2005) Effects of N-acylethanolamines on the respiratory chain and production of reactive oxygen species in heart mitochondria. FEBS Lett. 579:4724-4728. [PM:16099457].
  51. Ohnishi, T. and Salerno, J. C. (2005) Conformation-driven and semiquinone-gated proton-pump mechanism in the NADH-ubiquinone oxidoreductase (complex I). FEBS Lett. 579:4555-4561. [PM:16098512].
  52. Caparros-Lefebvre, D. and Lees, A. J. (2005) Atypical unclassifiable parkinsonism on Guadeloupe: an environmental toxic hypothesis. Mov Disord. 20 Suppl 12:S114-S118. [PM:16092100].
  53. Saborido, A., Soblechero, L., and Megias, A. (2005) Isolated respiring heart mitochondria release reactive oxygen species in states 4 and 3. Free Radic. Res. 39:921-931. [PM:16087473].
  54. Shang, T., Joseph, J., Hillard, C. J., and Kalyanaraman, B. (2005) Death-associated protein kinase as a sensor of mitochondrial membrane potential-Role of lysosome in mitochondrial toxin induced cell death. J. Biol. Chem. 280:34644-34653. [PM:16085644].
  55. Champy, P., Melot, A., Guerineau, E., V, Gleye, C., Fall, D., Hoglinger, G. U., Ruberg, M., Lannuzel, A., Laprevote, O., Laurens, A., and Hocquemiller, R. (2005) Quantification of acetogenins in Annona muricata linked to atypical parkinsonism in guadeloupe. Mov Disord. 20:1629-1633. [PM:16078200].
  56. Hinchliffe, P. and Sazanov, L. A. (2005) Organization of iron-sulfur clusters in respiratory complex I. Science 309:771-774. [PM:16051796].
  57. Tormo, J. R., DePedro, N., Royo, I., Barrachina, I., Zafra-Polo, M. C., Cuadrillero, C., Hernandez, P., Cortes, D., and Pelaez, F. (2005) In vitro antitumor structure-activity relationships of threo/trans/threo/trans/erythro bis-tetrahydrofuranic acetogenins: correlations with their inhibition of mitochondrial complex I. Oncol. Res. 15:129-138. [PM:16050134].
  58. Esteitie, N., Hinttala, R., Wibom, R., Nilsson, H., Hance, N., Naess, K., Tear-Fahnehjelm, K., von Dobeln, U., Majamaa, K., and Larsson, N. G. (2005) Secondary metabolic effects in complex I deficiency. Ann. Neurol. 58:544-552. [PM:16044424].
  59. Brandt, U., Abdrakhmanova, A., Zickermann, V., Galkin, A., Drose, S., Zwicker, K., and Kerscher, S. (2005) Structure-function relationships in mitochondrial complex I of the strictly aerobic yeast Yarrowia lipolytica. Biochem. Soc. Trans. 33:840-844. [PM:16042611].
  60. Friedrich, T., Stolpe, S., Schneider, D., Barquera, B., and Hellwig, P. (2005) Ion translocation by the Escherichia coli NADH:ubiquinone oxidoreductase (complex I). Biochem. Soc. Trans. 33:836-839. [PM:16042610].
  61. Leshinsky-Silver, E., Lev, D., Tzofi-Berman, Z., Cohen, S., Saada, A., Yanoov-Sharav, M., Gilad, E., and Lerman-Sagie, T. (2005) Fulminant neurological deterioration in a neonate with Leigh syndrome due to a maternally transmitted missense mutation in the mitochondrial ND3 gene. Biochem. Biophys. Res. Commun. 334:582-587. [PM:16023078].
  62. Melo, A. M., Lobo, S. A., Sousa, F. L., Fernandes, A. S., Pereira, M. M., Hreggvidsson, G. O., Kristjansson, J. K., Saraiva, L. M., and Teixeira, M. (2005) A nhaD Na+/H+ antiporter and a pcd homologues are among the Rhodothermus marinus complex I genes. Biochim. Biophys. Acta 1709:95-103. [PM:16023073].
  63. Blakely, E. L., Mitchell, A. L., Fisher, N., Meunier, B., Nijtmans, L. G., Schaefer, A. M., Jackson, M. J., Turnbull, D. M., and Taylor, R. W. (2005) A mitochondrial cytochrome b mutation causing severe respiratory chain enzyme deficiency in humans and yeast. FEBS J. 272:3583-3592. [PM:16008558].
  64. Ushakova, A. V., Duarte, M., Vinogradov, A. D., and Videira, A. (2005) The 29.9kDa Subunit of Mitochondrial Complex I is Involved in the Enzyme Active/De-active Transitions. J. Mol. Biol. 351:327-333. [PM:16005890].
  65. Wang, G., Qi, C., Fan, G. H., Zhou, H. Y., and Chen, S. D. (2005) PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex I inhibitor, rotenone. FEBS Lett. 579:4005-4011. [PM:16004991].
  66. Bharath, S. and Andersen, J. K. (2005) Glutathione depletion in a midbrain-derived immortalized dopaminergic cell line results in limited tyrosine nitration of mitochondrial complex I subunits: implications for Parkinson's disease. Antioxid. Redox. Signal. 7:900-910. [PM:15998245].
  67. Sindhu, K. M., Saravanan, K. S., and Mohanakumar, K. P. (2005) Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion. Brain Res. 1051:25-34. [PM:15992782].
  68. Da Sylva, T. R., Connor, A., Mburu, Y., Keystone, E., and Wu, G. E. (2005) Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes. Arthritis Res. Ther. 7:R844-R851. [PM:15987486].
  69. Kao, M.-C., S., Nakamaru-Ogiso, E., Matsuno-Yagi, A., and Yagi, T. (2005) Characterization of the Membrane Domain Subunit NuoK (ND4L) of the NADH-Quinone Oxidoreductase from Escherichia coli . Biochemistry 44:9545-9554. [PM:15996109]
  70. Xie, Y. X., Bezard, E., and Zhao, B. L. (2005) Investigating the receptor-independent neuroprotective mechanisms of nicotine in mitochondria. J. Biol. Chem. 280:32405-32412. [PM:15985439].
  71. Galkin, A. and Brandt, U. (2005) Superoxide radical formation by pure complex I (NADH: Ubiquinone oxidoreductase) from Yarrowia lipolytica. J. Biol. Chem. 280:30129-30135. [PM:15985426].
  72. Dinopoulos, A., Smeitink, J., and Ter Laak, H. (2005) Unusual features of mitochondrial degeneration in skeletal muscle of patients with nuclear complex I mutation. Acta Neuropathol. (Berl) 110:199-202. [PM:15981016].
  73. Amarneh, B. and Vik, S. B. (2005) Direct Transfer of NADH From Malate Dehydrogenase to Complex I in Escherichia coli. Cell Biochem. Biophys. 42:251-262. [PM:15976458].
  74. Petruzzella, V., Panelli, D., Torraco, A., Stella, A., and Papa, S. (2005) Mutations in the NDUFS4 gene of mitochondrial complex I alter stability of the splice variants. FEBS Lett. 579:3770-3776. [PM:15975579].
  75. Mitchell, A. L., Elson, J. L., Howell, N., Taylor, R. W., and Turnbull, D. M. (2005) Sequence Variation In Mitochondrial Complex I Genes: Mutation Or Polymorphism? J. Med. Genet. [PM:15972314].
  76. Wu, G. J., Tai, Y. T., Chen, T. L., Lin, L. L., Ueng, Y. F., and Chen, R. M. (2005) Propofol Specifically Inhibits Mitochondrial Membrane Potential but Not Complex I NADH Dehydrogenase Activity, Thus Reducing Cellular ATP Biosynthesis and Migration of Macrophages. Ann. N. Y. Acad. Sci. 1042:168-176. [PM:15965060].
  77. Bai, Y., Park, J. S., Deng, J. H., Li, Y., and Hu, P. (2005) Restoration of mitochondrial function in cells with complex I deficiency. Ann. N. Y. Acad. Sci. 1042:25-35. [PM:15965042].
  78. Del Arenal, I. P., Rubio, M. E., Ramirez, J., Rendon, J. L., and Escamilla, J. E. (2005) Cyanide-resistant respiration in Taenia crassiceps metacestode (cysticerci) is explained by the H2O2-producing side-reaction of respiratory complex I with O2. Parasitol. Int. 54:185-193. [PM:15958286].
  79. Duarte, M., Schulte, U., Ushakova, A. V., and Videira, A. (2005) Neurospora strains harboring mitochondrial disease-associated mutations in iron-sulfur subunits of complex I. Genetics 171:91-99. [PM:15956670].
  80. Naoi, M., Maruyama, W., Shamoto-Nagai, M., Yi, H., Akao, Y., and Tanaka, M. (2005) Oxidative stress in mitochondria: decision to survival and death of neurons in neurodegenerative disorders. Mol. Neurobiol. 31:81-94. [PM:15953813].
  81. Mus, F., Cournac, L., Cardettini, V., Caruana, A., and Peltier, G. (2005) Inhibitor studies on non-photochemical plastoquinone reduction and H2 photoproduction in Chlamydomonas reinhardtii. Biochim. Biophys. Acta 1708:322-332. [PM:15950924].
  82. Ho, P. W., Chan, D. Y., Kwok, K. H., Chu, A. C., Ho, J. W., Kung, M. H., Ramsden, D. B., and Ho, S. L. (2005) Methyl-4-phenylpyridinium ion modulates expression of mitochondrial uncoupling proteins 2, 4, and 5 in catecholaminergic (SK-N-SH) cells. J. Neurosci. Res. 81:261-268. [PM:15948157].
  83. Sarkar, M., Das, S., Bandyopadhaya, A., Ray, K., and Chaudhuri, K. (2005) Upregulation of human mitochondrial NADH dehydrogenase subunit 5 in intestinal epithelial cells is modulated by Vibrio cholerae pathogenesis. FEBS Lett. 579:3449-3460. [PM:15946665].
  84. van Straaten, H. L., van Tintelen, J. P., Trijbels, J. M., Van den Heuvel, L. P., Troost, D., Rozemuller, J. M., Duran, M., de Vries, L. S., Schuelke, M., and Barth, P. G. (2005) Neonatal Lactic Acidosis, Complex I/IV Deficiency, and Fetal Cerebral Disruption. Neuropediatrics 36:193-199. [PM:15944905].
  85. Darie, C. C., Biniossek, M. L., Winter, V., Mutschler, B., and Haehnel, W. (2005) Isolation and structural characterization of the Ndh complex from mesophyll and bundle sheath chloroplasts of Zea mays. FEBS J. 272:2705-2716. [PM:15943805].
  86. Sinegina, L., Wikstrom, M., Verkhovsky, M. I., and Verkhovskaya, M. L. (2005) Activation of Isolated NADH:Ubiquinone Reductase I (Complex I) from Escherichia coli by Detergent and Phospholipids. Recovery of Ubiquinone Reductase Activity and Changes in EPR Signals of Iron-Sulfur Clusters. Biochemistry 44:8500-8506. [PM:15938640].
  87. Saravanan, K. S., Sindhu, K. M., and Mohanakumar, K. P. (2005) Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease. Brain Res. 1049:147-155. [PM:15936733].
  88. Perales, M., Eubel, H., Heinemeyer, J., Colaneri, A., Zabaleta, E., and Braun, H. P. (2005) Disruption of a Nuclear Gene Encoding a Mitochondrial Gamma Carbonic Anhydrase Reduces Complex I and Supercomplex I+III2 Levels and Alters Mitochondrial Physiology in Arabidopsis. J. Mol. Biol. 350:263-277. [PM:15935378].
  89. Moon, Y., Lee, K. H., Park, J. H., Geum, D., and Kim, K. (2005) Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10. J. Neurochem. 93:1199-1208. [PM:15934940].
  90. Tremblay, M. S. and Sames, D. (2005) A new fluorogenic transformation: development of an optical probe for coenzyme Q. Org. Lett. 7:2417-2420. [PM:15932212].
  91. Hossain, K. F., Sen, T., Maiti, A. K., Jana, S., Chatterjee, U., and Chakrabarti, S. (2005) Inhibition of rat brain mitochondrial electron transport chain activity by dopamine oxidation products during extended in vitro incubation: Implications for Parkinson's disease. Biochim. Biophys. Acta 1741:65-74. [PM:15925494].
  92. Augereau, O., Claverol, S., Boudes, N., Basurko, M. J., Bonneu, M., Rossignol, R., Mazat, J. P., Letellier, T., and Dachary-Prigent, J. (2005) Identification of tyrosine-phosphorylated proteins of the mitochondrial oxidative phosphorylation machinery. Cell Mol. Life Sci. 62:1478-1488. [PM:15924266].
  93. Velazquez, I., Nakamaru-Ogiso, E., Yano, T., Ohnishi, T., and Yagi, T. (2005) Amino acid residues associated with cluster N3 in the NuoF subunit of the proton-translocating NADH-quinone oxidoreductase from Escherichia coli FEBS Lett. 579:3164-3168.[PM:15922336].
  94. Khaidakov, M., Chavannes-Turesky, N., Cooney, C. A., Dupont-Versteegden, E. E., Kennedy, R. H., Siegel, E. R., Khaidakova, G., and Shmookler Reis, R. J. (2005) Contribution of de novo point mutations to the overall mutational burden in mitochondrial DNA of adult rats. Exp. Gerontol. 40:396-402. [PM:15919591].
  95. Hirst, J. (2005) Energy transduction by respiratory complex I - an evaluation of current knowledge. Biochem. Soc. Trans. 33:525-529. [PM:15916556].
  96. Grammatopoulos, T. N., Ahmadi, F., Jones, S. M., Fariss, M. W., Weyhenmeyer, J. A., and Zawada, W. M. (2005) Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death. Brain Res. 1045:64-71. [PM:15910763].
  97. Sanz, A., Caro, P., Ibanez, J., Gomez, J., Gredilla, R., and Barja, G. (2005) Dietary restriction at old age lowers mitochondrial oxygen radical production and leak at complex I and oxidative DNA damage in rat brain. J. Bioenerg. Biomembr. 37:83-90. [PM:15906153].
  98. Garcia, N., Correa, F., and Chavez, E. (2005) On the role of the respiratory complex I on membrane permeability transition. J. Bioenerg. Biomembr. 37:17-23. [PM:15906145].
  99. Ohnishi, S. T., Ohnishi, T., Muranaka, S., Fujita, H., Kimura, H., Uemura, K., Yoshida, K., and Utsumi, K. (2005) A possible site of superoxide generation in the complex I segment of rat heart mitochondria. J. Bioenerg. Biomembr. 37:1-15. [PM:15906144].
  100. Ladha, J. S., Tripathy, M. K., and Mitra, D. (2005) Mitochondrial complex I activity is impaired during HIV-1-induced T-cell apoptosis. Cell Death. Differ. 12:1417-1428. [PM:15905875].
  101. Molina-Jimenez, M. F., Sanchez-Reus, M. I., Cascales, M., Andres, D., and Benedi, J. (2005) Effect of fraxetin on antioxidant defense and stress proteins in human neuroblastoma cell model of rotenone neurotoxicity. Comparative study with myricetin and N-acetylcysteine. Toxicol. Appl. Pharmacol. [PM:15904944].
  102. Koopman, W. J., Visch, H. J., Verkaart, S., van den Heuvel, L. W., Smeitink, J. A., and Willems, P. H. (2005) MITOCHONDRIAL NETWORK COMPLEXITY AND PATHOLOGICAL DECREASE IN COMPLEX I ACTIVITY ARE TIGHTLY CORRELATED IN ISOLATED HUMAN COMPLEX I DEFICIENCY. Am. J. Physiol Cell Physiol 289:C881-890. [PM:15901599].
  103. Zeevalk, G. D. and Bernard, L. P. (2005) Energy status, ubiquitin proteasomal function, and oxidative stress during chronic and acute complex I inhibition with rotenone in mesencephalic cultures. Antioxid. Redox. Signal. 7:662-672. [PM:15890011].
  104. Dukes, A. A., Korwek, K. M., and Hastings, T. G. (2005) The effect of endogenous dopamine in rotenone-induced toxicity in PC12 cells. Antioxid. Redox. Signal. 7:630-638. [PM:15890007].
  105. Kokaze, A., Ishikawa, M., Matsunaga, N., Yoshida, M., Makita, R., Satoh, M., Teruya, K., Sekiguchi, K., Masuda, Y., Harada, M., Uchida, Y., and Takashima, Y. (2005) Longevity-associated NADH dehydrogenase subunit-2 polymorphism and serum electrolyte levels in middle-aged obese Japanese men. Mech. Ageing Dev. 126:705-709. [PM:15888325].
  106. Baracca, A., Solaini, G., Sgarbi, G., Lenaz, G., Baruzzi, A., Schapira, A. H., Martinuzzi, A., and Carelli, V. (2005) Severe impairment of complex I-driven adenosine triphosphate synthesis in leber hereditary optic neuropathy cybrids. Arch. Neurol. 62:730-736. [PM:15883259].
  107. Scarlett, D. J., Herst, P. M., and Berridge, M. V. (2005) Multiple proteins with single activities or a single protein with multiple activities: The conundrum of cell surface NADH oxidoreductases. Biochim. Biophys. Acta 1708:108-119. [PM:15882838].
  108. Lin, P. C., Puhar, A., Turk, K., Piligkos, S., Bill, E., Neese, F., and Steuber, J. (2005) A vertebrate-type ferredoxin domain in the Na+ -translocating NADH dehydrogenase from vibrio cholerae. J. Biol. Chem. 280:22560-22563. [PM:15870079].
  109. Marques, I., Duarte, M., Assuncao, J., Ushakova, A. V., and Videira, A. (2005) Composition of complex I from Neurospora crassa and disruption of two "accessory" subunits. Biochim. Biophys. Acta 1707:211-220. [PM:15863099].
  110. Duval, R. A., Duret, P., Lewin, G., Peris, E., and Hocquemiller, R. (2005) Semisynthesis and biological activity of aminoacyl triesters of squamocin, an annonaceous acetogenin. Bioorg. Med. Chem. 13:3773-3781. [PM:15863004].
  111. Kudin, A. P., Debska-Vielhaber, G., and Kunz, W. S. (2005) Characterization of superoxide production sites in isolated rat brain and skeletal muscle mitochondria. Biomed. Pharmacother. 59:163-168. [PM:15862710].
  112. Dietrich, J. B., Mangeol, A., Revel, M. O., Burgun, C., Aunis, D., and Zwiller, J. (2005) Acute or repeated cocaine administration generates reactive oxygen species and induces antioxidant enzyme activity in dopaminergic rat brain structures. Neuropharmacology 48:965-974. [PM:15857623].
  113. Itoh, S., Lemay, S., Osawa, M., Che, W., Duan, Y., Tompkins, A., Brookes, P. S., Sheu, S. S., and Abe, J. I. (2005) Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappa B activation in endothelial cells. J. Biol. Chem. 280:26383-26396. [PM:15855164].
  114. Mamelak, A. J., Kowalski, J., Murphy, K., Yadava, N., Zahurak, M., Kouba, D. J., Howell, B. G., Tzu, J., Cummins, D. L., Liegeois, N. J., Berg, K., and Sauder, D. N. (2005) Downregulation of NDUFA1 and other oxidative phosphorylation-related genes is a consistent feature of basal cell carcinoma. Exp. Dermatol. 14:336-348. [PM:15854127].
  115. Pineau, B., Mathieu, C., Gerard-Hirne, C., De Paepe, R., and Chetrit, P. (2005) Targeting the NAD7 subunit to mitochondria restores a functional complex I and a wild type phenotype in the Nicotiana sylvestris CMSII mutant lacking nad7. J. Biol. Chem. 280:25994-26001. [PM:15849190].
  116. Schilling, B., Aggeler, R., Schulenberg, B., Murray, J., Row, R. H., Capaldi, R. A., and Gibson, B. W. (2005) Mass spectrometric identification of a novel phosphorylation site in subunit NDUFA10 of bovine mitochondrial complex I. FEBS Lett. 579:2485-2490. [PM:15848193].
  117. Gabaldon, T., Rainey, D., and Huynen, M. A. (2005) Tracing the Evolution of a Large Protein Complex in the Eukaryotes, NADH:Ubiquinone Oxidoreductase (Complex I). J. Mol. Biol. 348:857-870. [PM:15843018].
  118. Maximo, V., Botelho, T., Capela, J., Soares, P., Lima, J., Taveira, A., Amaro, T., Barbosa, A. P., Preto, A., Harach, H. R., Williams, D., and Sobrinho-Simoes, M. (2005) Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid. Br. J. Cancer 92:1892-1898. [PM:15841082].
  119. Burgdorf, T., van der, L. E., Bernhard, M., Yin, Q. Y., Back, J. W., Hartog, A. F., Muijsers, A. O., de Koster, C. G., Albracht, S. P., and Friedrich, B. (2005) The Soluble NAD+-Reducing [NiFe]-Hydrogenase from Ralstonia eutropha H16 Consists of Six Subunits and Can Be Specifically Activated by NADPH. J. Bacteriol. 187:3122-3132. [PM:15838039].
  120. Votyakova, T. V. and Reynolds, I. J. (2005) Ca-induced permeabilization promotes free radical release from rat brain mitochondria with partially inhibited complex I. J. Neurochem. 93:526-537. [PM:15836612].
  121. Martin, M. A., Blazquez, A., Gutierrez-Solana, L. G., Fernandez-Moreira, D., Briones, P., Andreu, A. L., Garesse, R., Campos, Y., and Arenas, J. (2005) Leigh syndrome associated with mitochondrial complex I deficiency due to a novel mutation in the NDUFS1 gene. Arch. Neurol. 62:659-661. [PM:15824269].
  122. Shiomi, K., Ui, H., Suzuki, H., Hatano, H., Nagamitsu, T., Takano, D., Miyadera, H., Yamashita, T., Kita, K., Miyoshi, H., Harder, A., Tomoda, H., and Omura, S. (2005) A gamma-lactone form nafuredin, nafuredin-gamma, also inhibits helminth complex I. J. Antibiot. (Tokyo) 58:50-55. [PM:15813180].
  123. Armstrong, F. A. (2005) Recent developments in dynamic electrochemical studies of adsorbed enzymes and their active sites. Curr. Opin. Chem. Biol. 9:110-117. [PM:15811794].
  124. Bogachev, A. V. and Verkhovsky, M. I. (2005) Na+-Translocating NADH:quinone oxidoreductase: progress achieved and prospects of investigations. Biochemistry (Mosc. ) 70:143-149. [PM:15807651].
  125. Vinogradov, A. D. and Grivennikova, V. G. (2005) Generation of superoxide-radical by the NADH:ubiquinone oxidoreductase of heart mitochondria. Biochemistry (Mosc. ) 70:120-127. [PM:15807648].
  126. Tarasiuk, J., Mazerski, J., Tkaczyk-Gobis, K., and Borowski, E. (2005) Molecular basis of the low activity of antitumor anthracenediones, mitoxantrone and ametantrone, in oxygen radical generation catalyzed by NADH dehydrogenase. Enzymatic and molecular modelling studies. Eur. J. Med. Chem. 40:321-328. [PM:15804531].
  127. Kosaka, T., Okuyama, R., Sun, W., Ogata, T., Harada, J., Araki, K., Izumi, M., Yoshida, T., Okuno, A., Fujiwara, T., Ohsumi, J., and Ichikawa, K. (2005) Identification of molecular target of amp-activated protein kinase activator by affinity purification and mass spectrometry. Anal. Chem. 77:2050-2055. [PM:15801737].
  128. White, M. Y., Cordwell, S. J., McCarron, H. C., Prasan, A. M., Craft, G., Hambly, B. D., and Jeremy, R. W. (2005) Proteomics of ischemia/reperfusion injury in rabbit myocardium reveals alterations to proteins of essential functional systems. Proteomics. 5:1395-1410. [PM:15800873].
  129. DiMauro, S. and Hirano, M. (2005) Mitochondrial encephalomyopathies: an update. Neuromuscul. Disord. 15:276-286. [PM:15792866].
  130. Testa, C. M., Sherer, T. B., and Greenamyre, J. T. (2005) Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures. Brain Res. Mol. Brain Res. 134:109-118. [PM:15790535].
  131. Weinstein, E. A., Yano, T., Li, L. S., Avarbock, D., Avarbock, A., Helm, D., McColm, A. A., Duncan, K., Lonsdale, J. T., and Rubin, H. (2005) Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs. Proc. Natl. Acad. Sci. U. S. A 102:4548-4553. [PM:15767566].
  132. Naini, A. B., Lu, J., Kaufmann, P., Bernstein, R. A., Mancuso, M., Bonilla, E., Hirano, M., and DiMauro, S. (2005) Novel mitochondrial DNA ND5 mutation in a patient with clinical features of MELAS and MERRF. Arch. Neurol. 62:473-476. [PM:15767514].
  133. Korenaga, M., Okuda, M., Otani, K., Wang, T., Li, Y., and Weinman, S. A. (2005) Mitochondrial dysfunction in hepatitis C. J. Clin. Gastroenterol. 39:S162-S166. [PM:15758653].
  134. Boxma, B., de Graaf, R. M., van der Staay, G. W., van Alen, T. A., Ricard, G., Gabaldon, T., van Hoek, A. H., Moon-van der Staay SY, Koopman, W. J., van Hellemond, J. J., Tielens, A. G., Friedrich, T., Veenhuis, M., Huynen, M. A., and Hackstein, J. H. (2005) An anaerobic mitochondrion that produces hydrogen. Nature 434:74-79. [PM:15744302].
  135. Kao, M.C., Di Bernardo, S., Nakamaru-Ogiso, E., Miyoshi, H., Matsuno-Yagi, A., and Yagi, T. (2005) Characterization of the Membrane Domain Subunit NuoJ (ND6) of theNADH-Quinone Oxidoreductase from Escherichia coli by Chromosomal DNA Manipulation. Biochemistry 44:3562-3571. [PM:15736965].
  136. Carroll, J., Fearnley, I. M., Skehel, J. M., Runswick, M. J., Shannon, R. J., Hirst, J., and Walker, J. E. (2005) The post-translational modifications of the nuclear encoded subunits of complex I from bovine heart mitochondria. Mol. Cell Proteomics. 4:693-699.[PM:15728260].
  137. Arteni, A. A., Nowaczyk, M., Lax, J., Kouril, R., Rogner, M., and Boekema, E. J. (2005) Single particle electron microscopy in combination with mass spectrometry to investigate novel complexes of membrane proteins. J. Struct. Biol. 149:325-331. [PM:15721586].
  138. Drahota, Z., Krivakova, P., Cervinkova, Z., Kmonickova, E., Lotkova, H., Kucera, O., and Houstek, J. (2005) Tert-butyl hydroperoxide selectively inhibits mitochondrial respiratory-chain enzymes in isolated rat hepatocytes. Physiol Res. 54:67-72. [PM:15717843].
  139. Hsu, M., Srinivas, B., Kumar, J., Subramanian, R., and Andersen, J. (2005) Glutathione depletion resulting in selective mitochondrial complex I inhibition in dopaminergic cells is via an NO-mediated pathway not involving peroxynitrite: implications for Parkinson's disease. J. Neurochem. 92:1091-1103. [PM:15715660].
  140. Dudkina, N. V., Eubel, H., Keegstra, W., Boekema, E. J., and Braun, H. P. (2005) Structure of a mitochondrial supercomplex formed by respiratory-chain complexes I and III. Proc. Natl. Acad. Sci. U. S. A 102:3225-3229. [PM:15713802].
  141. Zoccarato, F., Toscano, P., and Alexandre, A. (2005) Dopamine-derived dopaminochrome promotes H202 release at mitochondrial complex 1. Stimulation by rotenone and control by Ca2+. Relevance to Parkinson's disease. J. Biol. Chem. 280:15587-15594. [PM:15710606].
  142. de Meer, K., Roef, M. J., de Klerk, J. B., Bakker, H. D., Smit, G. P., and Poll-The BT (2005) Increasing fat in the diet does not improve muscle performance in patients with mitochondrial myopathy due to complex I deficiency. J. Inherit. Metab Dis. 28:95-98. [PM:15702410].
  143. Wang, X. J. and Xu, J. X. (2005) Possible involvement of Ca2+ signaling in rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells. Neurosci. Lett. 376:127-132. [PM:15698934].
  144. Kotake, Y., Taguchi, R., Okuda, K., Sekiya, Y., Tasaki, Y., Hirobe, M., and Ohta, S. (2005) Neuroprotective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline on cultured rat mesencephalic neurons in the presence or absence of various neurotoxins. Brain Res. 1033:143-150. [PM:15694918].
  145. Bastianon, C., Zanoni, R., Miolo, G., Caffieri, S., and Reddi, E. (2005) Mitochondria and plasma membrane as targets of UVA-induced toxicity of neuroleptic drugs fluphenazine, perphenazine and thioridazine. Int. J. Biochem. Cell Biol. 37:901-908. [PM:15694848].
  146. Mathews, C. E., Leiter, E. H., Spirina, O., Bykhovskaya, Y., Gusdon, A. M., Ringquist, S., and Fischel-Ghodsian, N. (2005) mt-Nd2 Allele of the ALR/Lt mouse confers resistance against both chemically induced and autoimmune diabetes. Diabetologia 48:261-267. [PM:15692809].
  147. Yano, T., Dunham, W. R., and Ohnishi, T. (2005) Characterization of the H+-Sensitive Ubisemiquinone Species (SQ(Nf)) and the Interaction with Cluster N2: New Insight into the Energy-Coupled Electron Transfer in Complex I. Biochemistry 44:1744-1754. [PM:15683258].
  148. Uhlmann, M. and Friedrich, T. (2005) EPR Signals Assigned to Fe/S Cluster N1c of the Escherichia coli NADH:Ubiquinone Oxidoreductase (Complex I) Derive from Cluster N1a. Biochemistry 44:1653-1658. [PM:15683249].
  149. Wang, X. J. and Xu, J. X. (2005) Salvianic acid A protects human neuroblastoma SH-SY5Y cells against MPP(+)-induced cytotoxicity. Neurosci. Res. 51:129-138. [PM:15681030].
  150. Nantapong, N., Otofuji, A., Migita, T., Adachi, O., Toyama, H., and Matsushita, K. (2005) Electron Transfer Ability from NADH to Menaquinone and from NADPH to Oxygen of Type II NADH Dehydrogenase of Corynebacterium glutamicum. Biosci. Biotechnol. Biochem. 69:149-159. [PM:15665480].
  151. Blakely, E. L., Silva, R. D., King, A., Schwarzer, V., Harrower, T., Dawidek, G., Turnbull, D. M., and Taylor, R. W. (2005) LHON/MELAS overlap syndrome associated with a mitochondrial MTND1 gene mutation. Eur. J. Hum. Genet. 13:623-627. [PM:15657614].
  152. Steyn, S. J., Pieterse, D. J., Mienie, L. J., and Van der Schyf, C. J. (2005) Measurement of mitochondrial respiration in permeabilized murine neuroblastoma (N-2alpha) cells, a simple and rapid in situ assay to investigate mitochondrial toxins. J. Biochem. Biophys. Methods 62:25-40. [PM:15656941].
  153. Martinez, B., Perez-Castillo, A., and Santos, A. (2005) The mitochondrial respiratory complex I is a target for 15 deoxy-delta-12,14-PGJ2 (15d-PGJ2) action. J. Lipid Res. 46:736-743. [PM:15654126].
  154. Koopman, W. J., Verkaart, S., Visch, H. J., Van Der Westhuizen, F. H., Murphy, M. P., van den Heuvel, L. W., Smeitink, J. A., and Willems, P. H. (2005) Inhibition of complex I of the electron transport chain causes oxygen radical-mediated mitochondrial outgrowth. Am. J. Physiol Cell Physiol 288:C1440-1450. [PM:15647387].
  155. Ohnishi, T., Johnson, J. E., Jr., Yano, T., LoBrutto, R., and Widger, W. R. (2005) Thermodynamic and EPR studies of slowly relaxing ubisemiquinone species in the isolated bovine heart complex I. FEBS Lett. 579:500-506. [PM:15642366].
  156. Ichimaru, N., Murai, M., Abe, M., Hamada, T., Yamada, Y., Makino, S., Nishioka, T., Makabe, H., Makino, A., Kobayashi, T., and Miyoshi, H. (2005) Synthesis and inhibition mechanism of Deltalac-acetogenins, a novel type of inhibitor of bovine heart mitochondrial complex I. Biochemistry 44:816-825. [PM:15641810].
  157. Quintanilla, M. E., Tampier, L., Valle-Prieto, A., Sapag, A., and Israel, Y. (2005) Complex I regulates mutant mitochondrial aldehyde dehydrogenase activity and voluntary ethanol consumption in rats. FASEB J. 19:36-42. [PM:15629893].
  158. Minnerop, M., Kornblum, C., Joe, A. Y., Tatsch, K., Kunz, W. S., Klockgether, T., Wullner, U., and Reinhardt, M. J. (2005) Dopamine transporter SPECT in patients with mitochondrial disorders. J. Neurol. Neurosurg. Psychiatry 76:118-120. [PM:15608010].
  159. Vyshkina, T., Banisor, I., Shugart, Y. Y., Leist, T. P., and Kalman, B. (2005) Genetic variants of Complex I in multiple sclerosis. J. Neurol. Sci. 228:55-64. [PM:15607211].
  160. Parker, W. D., Jr. and Parks, J. K. (2005) Mitochondrial ND5 mutations in idiopathic Parkinson's disease. Biochem. Biophys. Res. Commun. 326:667-669. [PM:15596151].
  161. Guera, A., Calatayud, A., Sabater, B., and Barreno, E. (2005) Involvement of the thylakoidal NADH-plastoquinone-oxidoreductase complex in the early responses to ozone exposure of barley (Hordeum vulgare L.) seedlings. J. Exp. Bot. 56:205-218. [PM:15557294].
  162. Kovacs, G. G., Hoftberger, R., Majtenyi, K., Horvath, R., Barsi, P., Komoly, S., Lassmann, H., Budka, H., and Jakab, G. (2005) Neuropathology of white matter disease in Leber's hereditary optic neuropathy. Brain 128:35-41.[PM:15483043].
  163. Schilling, B., Bharath, M. M. S., Row, R. H., Murray, J., Cusack, M. P., Capaldi, R. A., Freed, C. R., Prasad, K. N., Andersen, J. K., and Gibson, B. W. (2005) Rapid purification and mass spectrometric characterization of mitochondrial NADH dehydrogenase (Complex I) from rodent brain and a dopaminergic neuronal cell line. Mol. Cell Proteomics. 4:84-96. [PM:15591592].
  164. Nakamaru-Ogiso, E., Yano, T., Yagi, T., and Ohnishi, T. (2005) Characterization of the iron-sulfur cluster N7(N1c) in the subunit NuoG of the proton-translocating NADH-quinone oxidoreductase from Escherichia coli. J. Biol. Chem. 280:301-307. [PM:15520003].
  165. Abu-Amero, K. K., Alzahrani, A. S., Zou, M., and Shi, Y. (2005) High frequency of somatic mitochondrial DNA mutations in human thyroid carcinomas and complex I respiratory defect in thyroid cancer cell lines. Oncogene 24:1455-1460. [PM:15608681].
  166. Waletko, A., Zwicker, K., Abdrakhmanova, A., Zickermann, V., Brandt, U., and Kerscher, S. (2005) Histidine 129 in the 75 kDa subunit of mitochondrial complex I from Yarrowia lipolytica is not a ligand for Fe4S4 cluster N5, but is required for catalytic activity. J. Biol. Chem. 280:5622-5625. [PM:15572358]
  167. Bunoust, O., Devin, A., Averet, N., Camougrand, N., and Rigoulet, M. (2005) Competition of electrons to enter the respiratory chain : A new regulatory mechanism of oxidative metabolism in Saccharomyces cerevisiae. J. Biol. Chem. 280:3407-3413. [PM:15557339].
  168. Reyes, A., Yang, M., Bowmaker, M., and Holt, I. J. (2005) Bidirectional replication initiates at sites throughout the mitochondrial genome of birds. J. Biol. Chem. 280:3242-3250. [PM:15557283].
  169. Eschemann, A., Galkin, A., Oettmeier, W., Brandt, U., and Kerscher, S. (2005) HDQ (1-hydroxy-2-dodecyl-4(1H)quinolone), a high affinity inhibitor for mitochondrial alternative NADH-dehydrogen. J. Biol. Chem. 280:3138-3142. [PM:15533932].
  170. Frost, M. T., Wang, Q., Moncada, S., and Singer, M. (2005) Hypoxia accelerates nitric oxide-dependent inhibition of mitochondrial complex I in activated macrophages. Am. J. Physiol Regul. Integr. Comp Physiol 288:R394-400. [PM:15486095].

  Return to the publications page