Publications (2013)

  1. Ellinghaus, P., Heisler, I., Unterschemmann, K., Haerter, M., Beck, H., Greschat, S., Ehrmann, A., Summer, H., Flamme, I., Oehme, F., Thierauch, K., Michels, M., Hess-Stumpp, H., and Ziegelbauer, K. (2013) BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I. Cancer Med. 2:611-624. [PM:24403227].
  2. Pei, H., Wan, X., Hu, W., Dong, X., and Li, B. (2013) Construction and detection of a novel type of recombinant human rAAV2/2-ND4. Eye Sci. 28:55-59. [PM:24396955].
  3. Bowden, S. A., Patel, H. P., Beebe, A., and McBride, K. L. (2013) Successful Medical Therapy for Hypophosphatemic Rickets due to Mitochondrial Complex I Deficiency Induced de Toni-Debre-Fanconi Syndrome. Case. Rep. Pediatr. 2013:354314- [PM:24386581].
  4. Corona, J. C., de Souza, S. C., and Duchen, M. R. (2013) PPARgamma activation rescues mitochondrial function from inhibition of complex I and loss of PINK1. Exp. Neurol. 253C:16-27. [PM:24374061].
  5. Mentzer, R. M., Jr., Wider, J., Perry, C. N., and Gottlieb, R. A. (2013) Reduction of Infarct Size by the Therapeutic Protein TAT-Ndi1 In Vivo. J. Cardiovasc. Pharmacol. Ther. [PM:24367006].
  6. Baran, I., Ionescu, D., Privitera, S., Scordino, A., Mocanu, M. M., Musumeci, F., Grasso, R., Gulino, M., Iftime, A., Tofolean, I. T., Garaiman, A., Goicea, A., Irimia, R., Dimancea, A., and Ganea, C. (2013) Mitochondrial respiratory complex I probed by delayed luminescence spectroscopy. J. Biomed. Opt. 18:127006- [PM:24365956].
  7. Bertsova, Y. V., Kostyrko, V. A., Baykov, A. A., and Bogachev, A. V. (2013) Localization-controlled specificity of FAD:threonine flavin transferases in Klebsiella pneumoniae and its implications for the mechanism of Na-translocating NADH:quinone oxidoreductase. Biochim. Biophys. Acta [PM:24361839].
  8. Minato, Y., Fassio, S. R., Reddekopp, R. L., and Hase, C. C. (2013) Inhibition of the sodium-translocating NADH-ubiquinone oxidoreductase [Na-NQR] decreases cholera toxin production in Vibrio cholerae O1 at the late exponential growth phase. Microb. Pathog. 66C:36-39. [PM:24361395].
  9. Guarani, V., Paulo, J., Zhai, B., Huttlin, E. L., Gygi, S. P., and Harper, J. W. (2013) TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial Complex I assembly factor through association with the MCIA complex. Mol. Cell Biol. [PM:24344204].
  10. Raule, N., Sevini, F., Li, S., Barbieri, A., Tallaro, F., Lomartire, L., Vianello, D., Montesanto, A., Moilanen, J. S., Bezrukov, V., Blanche, H., Hervonen, A., Christensen, K., Deiana, L., Gonos, E. S., Kirkwood, T. B., Kristensen, P., Leon, A., Pelicci, P. G., Poulain, M., Rea, I. M., Remacle, J., Robine, J. M., Schreiber, S., Sikora, E., Eline, S. P., Spazzafumo, L., Antonietta, S. M., Toussaint, O., Vaupel, J. W., Rose, G., Majamaa, K., Perola, M., Johnson, T. E., Bolund, L., Yang, H., Passarino, G., and Franceschi, C. (2013) The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific. Aging Cell [PM:24341918].
  11. Jenkins, Y., Sun, T. Q., Markovtsov, V., Foretz, M., Li, W., Nguyen, H., Li, Y., Pan, A., Uy, G., Gross, L., Baltgalvis, K., Yung, S. L., Gururaja, T., Kinoshita, T., Owyang, A., Smith, I. J., McCaughey, K., White, K., Godinez, G., Alcantara, R., Choy, C., Ren, H., Basile, R., Sweeny, D. J., Xu, X., Issakani, S. D., Carroll, D. C., Goff, D. A., Shaw, S. J., Singh, R., Boros, L. G., Laplante, M. A., Marcotte, B., Kohen, R., Viollet, B., Marette, A., Payan, D. G., Kinsella, T. M., and Hitoshi, Y. (2013) AMPK Activation through Mitochondrial Regulation Results in Increased Substrate Oxidation and Improved Metabolic Parameters in Models of Diabetes. PLoS. ONE. 8:e81870- [PM:24339975].
  12. Knuuti, J., Belevich, G., Sharma, V., Bloch, D. A., and Verkhovskaya, M. (2013) A single amino acid residue controls ROS production in the respiratory Complex I from Escherichia coli. Mol. Microbiol. 90:1190-1200. [PM:24325249].
  13. Massoz, S., Larosa, V., Plancke, C., Lapaille, M., Bailleul, B., Pirotte, D., Radoux, M., Leprince, P., Coosemans, N., Matagne, R. F., Remacle, C., and Cardol, P. (2013) Inactivation of genes coding for mitochondrial Nd7 and Nd9 complex I subunits in Chlamydomonas reinhardtii. Impact of complex I loss on respiration and energetic metabolism. Mitochondrion. [PM:24316185].
  14. Levy, R. J., Rios, P. G., Akman, H. O., Sciacco, M., Vivo, D. C., and DiMauro, S. (2013) Long Survival in Patients With Leigh Syndrome and the m.10191T>C Mutation in MT-ND3: A Case Report and Review of the Literature. J. Child Neurol. [PM:24284231].
  15. Calabrese, C., Iommarini, L., Kurelac, I., Calvaruso, M. A., Capristo, M., Lollini, P. L., Nanni, P., Bergamini, C., Nicoletti, G., Giovanni, C. D., Ghelli, A., Giorgio, V., Caratozzolo, M. F., Marzano, F., Manzari, C., Betts, C. M., Carelli, V., Ceccarelli, C., Attimonelli, M., Romeo, G., Fato, R., Rugolo, M., Tullo, A., Gasparre, G., and Porcelli, A. M. (2013) Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells. Cancer Metab 1:11- [PM:24280190].
  16. Hielscher, R., Yegres, M., Voicescu, M., Gnandt, E., Friedrich, T., and Hellwig, P. (2013) Characterization of two quinone radicals in the NADH:ubiquinone oxidoreductase from Escherichia coli by a combined fluorescence spectroscopic and electrochemical approach. Biochemistry [PM:24279322].
  17. Simeone, K. A., Matthews, S. A., Samson, K. K., and Simeone, T. A. (2013) Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model of acute temporal lobe seizures. Exp. Neurol. [PM:24270080].
  18. Brendel, A., Renziehausen, J., Behl, C., and Hajieva, P. (2013) Downregulation of PMCA2 increases the vulnerability of midbrain neurons to mitochondrial complex I inhibition. Neurotoxicology [PM:24269647].
  19. Onukwufor, J. O., MacDonald, N., Kibenge, F., Stevens, D., and Kamunde, C. (2013) Hypoxia-cadmium interactions on rainbow trout (Oncorhynchus mykiss) mitochondrial bioenergetics: attenuation of hypoxia-induced proton leak by low doses of cadmium. J. Exp. Biol. [PM:24265424].
  20. Simcox, E. M., Reeve, A., and Turnbull, D. (2013) Monitoring mitochondrial dynamics and complex I dysfunction in neurons: implications for Parkinson's disease. Biochem. Soc. Trans. 41:1618-1624. [PM:24256264].
  21. Granados-Castro, L. F., Rodriguez-Rangel, D. S., Montano, M., Ramos, C., and Pedraza-Chaverri, J. (2013) Wood smoke exposure induces a decrease in respiration parameters and in the activity of respiratory complexes I and IV in lung mitochondria from guinea pigs. Environ. Toxicol. [PM:24255020].
  22. Genova, M. L. and Lenaz, G. (2013) Functional role of mitochondrial respiratory supercomplexes. Biochim. Biophys. Acta [PM:24246637].
  23. Im, A. R., Kim, Y. H., Uddin, M. R., Chae, S., Lee, H. W., Kim, Y. S., and Lee, M. Y. (2013) Neuroprotective Effects of Lycium chinense Miller Against Rotenone-Induced Neurotoxicity in PC12 Cells. Am. J. Chin Med. 41:1343-1359. [PM:24228605].
  24. Yamamoto, H. and Shikanai, T. (2013) In Planta Mutagenesis of Src Homology 3 Domain-like Fold of NdhS, a Ferredoxin-binding Subunit of the Chloroplast NADH Dehydrogenase-like Complex in Arabidopsis: A Conserved Arg193 Plays a Critical Role in Ferredoxin Binding. J. Biol. Chem. [PM:24225949].
  25. Mileykovskaya, E. and Dowhan, W. (2013) Cardiolipin-dependent formation of mitochondrial respiratory supercomplexes. Chem. Phys. Lipids [PM:24220496].
  26. Francis, B. M., Yang, J., Song, B. J., Gupta, S., Maj, M., Bazinet, R., Robinson, B., and Mount, H. T. (2013) Reduced Levels of Mitochondrial Complex I Subunit NDUFB8 and Linked Complex I + III Oxidoreductase Activity in the TgCRND8 Mouse Model of Alzheimer's Disease. J. Alzheimers. Dis. [PM:24217272].
  27. Verkhovskaya, M. and Wikstrom, M. (2013) Oxidoreduction properties of bound ubiquinone in Complex I from Escherichia coli. Biochim. Biophys. Acta [PM:24216024].
  28. Tamilselvam, K., Braidy, N., Manivasagam, T., Essa, M. M., Prasad, N. R., Karthikeyan, S., Thenmozhi, A. J., Selvaraju, S., and Guillemin, G. J. (2013) Neuroprotective effects of hesperidin, a plant flavanone, on rotenone-induced oxidative stress and apoptosis in a cellular model for Parkinson's disease. Oxid. Med. Cell Longev. 2013:102741- [PM:24205431].
  29. Andrews, B., Carroll, J., Ding, S., Fearnley, I. M., and Walker, J. E. (2013) Assembly factors for the membrane arm of human complex I. Proc. Natl. Acad. Sci. U. S. A 110:18934-18939. [PM:24191001].
  30. Drahota, Z., Palenickova, E., Endlicher, R., Milerova, M., Brejchova, J., Vosahlikova, M., Svoboda, P., Kazdova, L., Kalous, M., Cervinkova, Z., and Cahova, M. (2013) Biguanides inhibit complex I, II and IV of rat liver mitochondria and modify their functional properties. Physiol Res. [PM:24182344].
  31. Wydro, M. M., Sharma, P., Foster, J. M., Bych, K., Meyer, E. H., and Balk, J. (2013) The Evolutionarily Conserved Iron-Sulfur Protein INDH1 Is Required for Complex I Assembly and Mitochondrial Translation in Arabidopsis. Plant Cell 25:4014-4027. [PM:24179128].
  32. Desquiret-Dumas, V., Gueguen, N., Leman, G., Baron, S., Nivet-Antoine, V., Chupin, S., Chevrollier, A., Vessieres, E., Ayer, A., Ferre, M., Bonneau, D., Henrion, D., Reynier, P., and Procaccio, V. (2013) Resveratrol Induces a Mitochondrial Complex I Dependent Increase in NADH Oxidation Responsible for Sirtuin Activation in Liver Cells. J. Biol. Chem. [PM:24178296].
  33. Iommarini, L., Kurelac, I., Capristo, M., Calvaruso, M. A., Giorgio, V., Bergamini, C., Ghelli, A., Nanni, P., De, G. C., Carelli, V., Fato, R., Lollini, P. L., Rugolo, M., Gasparre, G., and Porcelli, A. M. (2013) Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment. Hum. Mol. Genet. [PM:24163135].
  34. Nouws, J., Te, B. H., Nijtmans, L. G., and Houten, S. M. (2013) ACAD9, a complex I assembly factor with a moonlighting function in fatty acid oxidation deficiencies. Hum. Mol. Genet. [PM:24158852].
  35. Rezvani, Z., Didari, E., Arastehkani, A., Ghodsinejad, V., Aryani, O., Kamalidehghan, B., and Houshmand, M. (2013) Fifteen novel mutations in the mitochondrial NADH dehydrogenase subunit 1, 2, 3, 4, 4L, 5 and 6 genes from Iranian patients with Leber's hereditary optic neuropathy (LHON). Mol. Biol. Rep. [PM:24158608].
  36. Peralta, S., Torraco, A., Wenz, T., Garcia, S., Diaz, F., and Moraes, C. T. (2013) Partial Complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage. Hum. Mol. Genet. [PM:24154540].
  37. Han, G., Wood, J. P., Chidlow, G., Mammone, T., and Casson, R. (2013) Mechanisms of Neuroprotection by Glucose in Rat Retinal Cell Cultures Subjected to Respiratory Inhibition. Invest Ophthalmol. Vis. Sci. [PM:24150756].
  38. Morino, M., Suzuki, T., Ito, M., and Krulwich, T. A. (2013) Purification and functional reconstitution of a seven-subunit Mrp-type Na+/H+ antiporter. J. Bacteriol. [PM:24142251].
  39. Gautier, C. A., Corti, O., and Brice, A. (2013) Mitochondrial dysfunctions in Parkinson's disease. Rev. Neurol. (Paris) [PM:24119854].
  40. Delmiro, A., Rivera, H., Garcia-Silva, M. T., Garcia-Consuegra, I., Martin-Hernandez, E., Quijada-Fraile, P., de Las Heras, R. S., Moreno-Izquierdo, A., Martin, M. A., Arenas, J., and Martinez-Azorin, F. (2013) Whole-Exome Sequencing Identifies a Variant of the Mitochondrial MT-ND1 Gene Associated with Epileptic Encephalopathy: West Syndrome Evolving to Lennox-Gastaut Syndrome. Hum. Mutat. [PM:24105702].
  41. He, Q., Wang, M., Petucci, C., Gardell, S. J., and Han, X. (2013) Rotenone induces reductive stress and triacylglycerol deposition in C2C12 cells. Int. J. Biochem. Cell Biol. 45:2749-2755. [PM:24104397].
  42. Slaska, B., Grzybowska-Szatkowska, L., Nisztuk, S., Surdyka, M., and Rozanska, D. (2013) Mitochondrial DNA polymorphism in genes encoding ND1, COI and CYTB in canine malignant cancers. Mitochondrial. DNA [PM:24102599].
  43. Moparthi, V. K., Kumar, B., Al-Eryani, Y., Sperling, E., Gorecki, K., Drakenberg, T., and Hagerhall, C. (2013) Functional role of the MrpA- and MrpD-homologous protein subunits in enzyme complexes evolutionary related to respiratory chain complex I. Biochim. Biophys. Acta 1837:178-185. [PM:24095649].
  44. Rhein, V. F., Carroll, J., Ding, S., Fearnley, I. M., and Walker, J. E. (2013) NDUFAF7 Methylates Arginine-85 in the NDUFS2 Subunit of Human Complex I. J. Biol. Chem. [PM:24089531].
  45. Schwarz, D., Schubert, H., Georg, J., Hess, W. R., and Hagemann, M. (2013) The Gene sml0013 of Synechocystis Species Strain PCC 6803 Encodes for a Novel Subunit of the NAD(P)H Oxidoreductase or Complex I That Is Ubiquitously Distributed among Cyanobacteria. Plant Physiol 163:1191-1202. [PM:24089436].
  46. Rezaee, A. R., Azadi, A., Houshmand, M., Mahmoodi, F., Purpak, Z., Safaei, S., Karimi, P., Ghabaee, M., and Sahraian, M. A. (2013) Mitochondrial and nuclear genes as the cause of complex I deficiency. Genet. Mol. Res. 12:3551-3554. [PM:24065688].
  47. Wray, C. D., Friederich, M. W., du, S. D., Pantaleo, S., Smet, J., Kucera, C., Fenton, L., Scharer, G., Van, C. R., and Van Hove, J. L. (2013) A new mutation in MT-ND1 m.3928G>C p.V208L causes Leigh disease with infantile spasms. Mitochondrion. [PM:24063851].
  48. Ji, K., Zheng, J., Sun, B., Liu, F., Shan, J., Li, D., Luo, Y. B., Zhao, Y., and Yan, C. (2013) Novel Mitochondrial C15620A Variant may Modulate the Phenotype of Mitochondrial G11778A Mutation in a Chinese Family with Leigh Syndrome. Neuromolecular. Med. [PM:24062162].
  49. Babot, M. and Galkin, A. (2013) Molecular mechanism and physiological role of active-deactive transition of mitochondrial complex I. Biochem. Soc. Trans. 41:1325-1330. [PM:24059527].
  50. Steffen, W. and Steuber, J. (2013) Cation transport by the respiratory NADH:quinone oxidoreductase (complex I): facts and hypotheses. Biochem. Soc. Trans. 41:1280-1287. [PM:24059520].
  51. Kmita, K. and Zickermann, V. (2013) Accessory subunits of mitochondrial complex I. Biochem. Soc. Trans. 41:1272-1279. [PM:24059519].
  52. Sazanov, L. A., Baradaran, R., Efremov, R. G., Berrisford, J. M., and Minhas, G. (2013) A long road towards the structure of respiratory complex I, a giant molecular proton pump. Biochem. Soc. Trans. 41:1265-1271. [PM:24059518].
  53. De-Mateo-Silleras, B., Alonso-Torre, S. R., Redondo-Del-Rio, P., Jeejeebhoy, K., and Mijan-de-la-Torre, A. (2013) Effect of nutritional support on mitochondrial complex I activity in malnourished patients with anorexia nervosa. Appl. Physiol Nutr. Metab 38:1093-1098. [PM:24053515].
  54. Hur, J. H., Bahadorani, S., Graniel, J., Koehler, C. L., Ulgherait, M., Rera, M., Jones, D. L., and Walker, D. W. (2013) Increased longevity mediated by yeast NDI1 expression in Drosophila intestinal stem and progenitor cells. Aging (Albany. NY) [PM:24038661].
  55. Shea, M. E., Juarez, O., Cho, J., and Barquera, B. (2013) Aspartic acid 397 in subunit B of the Na+-pumping NADH: quinone oxidoreductase from Vibrio cholerae forms part of a sodium binding site, is involved in cation selectivity and affects cation binding site cooperativity. J. Biol. Chem. [PM:24030824].
  56. Jaokar, T. M., Patil, D. P., Shouche, Y. S., Gaikwad, S. M., and Suresh, C. G. (2013) Human mitochondrial NDUFS3 protein bearing Leigh syndrome mutation is more prone to aggregation than its wild-type. Biochimie [PM:24028823].
  57. Braidy, N., Gai, W. P., Xu, Y. H., Sachdev, P., Guillemin, G. J., Jiang, X. M., Ballard, J. W., Horan, M. P., Fang, Z. M., Chong, B. H., and Chan, D. K. (2013) Alpha-Synuclein Transmission and Mitochondrial Toxicity in Primary Human Foetal Enteric Neurons In Vitro. Neurotox. Res. [PM:24026637].
  58. Quinlan, C. L., Perevoshchikova, I. V., Hey-Mogensen, M., Orr, A. L., and Brand, M. D. (2013) Sites of reactive oxygen species generation by mitochondria oxidizing different substrates. Redox. Biol. 1:304-312. [PM:24024165].
  59. Das, K. C. (2013) Hyperoxia Decreases Glycolytic Capacity, Glycolytic Reserve and Oxidative Phosphorylation in MLE-12 Cells and Inhibits Complex I and II Function, but Not Complex IV in Isolated Mouse Lung Mitochondria. PLoS. ONE. 8:e73358- [PM:24023862].
  60. Virzintiene, E., Moparthi, V. K., Al-Eryani, Y., Shumbe, L., Gorecki, K., and Hagerhall, C. (2013) Structure and function of the C-terminal domain of MrpA in the Bacillus subtilis Mrp-antiporter comp. FEBS Lett. 587:3341-3347. [PM:24021651].
  61. Wang, H. N., Chen, H. D., Chen, K. Y., Xiao, J. F., He, K., Xiang, G. A., and Xie, X. (2013) Highly expressed MT-ND3 positively associated with histological severity of hepatic steatosis. APMIS [PM:24020820].
  62. Assereto, S., Robbiano, A., Di, R. M., Rossi, A., Cassandrini, D., Panicucci, C., Brigati, G., Biancheri, R., Bruno, C., Minetti, C., Trucks, H., Sander, T., Zara, F., and Gazzerro, E. (2013) Functional characterization of the c.462delA mutation in the NDUFS4 subunit gene of mitochondrial complex I. Clin. Genet. [PM:24020637].
  63. Zhang, Q., Raje, V., Yakovlev, V. A., Yacoub, A., Szczepanek, K., Meier, J., Derecka, M., Chen, Q., Hu, Y., Sisler, J., Hamed, H., Lesnefsky, E. J., Jr., Valerie, K., Dent, P., and Larner, A. C. (2013) Mitochondrial-Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727. J. Biol. Chem. [PM:24019511].
  64. Nedielkov, R., Steffen, W., Steuber, J., and Moller, H. M. (2013) NMR reveals double occupancy of quinone-type ligands in the catalytic quinone binding site of the Na+-translocating NADH:quinone oxidoreductase from Vibrio cholerae. J. Biol. Chem. [PM:24003222].
  65. Hamalainen, R. H., Manninen, T., Koivumaki, H., Kislin, M., Otonkoski, T., and Suomalainen, A. (2013) Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model.. Proc. Natl. Acad. Sci. U. S. A 110:E3622-E3630. [PM:24003133].
  66. Garcia-Garcia, A., Annandurai, A., Burns, M., Chen, H., Zhou, Y., and Franco, R. (2013) Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP+-induced apoptosis but not rotenone or 6-hydroxydopamine toxicity.. Toxicol. Sci. [PM:23997112].
  67. Nouws, J., Wibrand, F., van den Brand, M., Venselaar, H., Duno, M., Lund, A. M., Trautner, S., Nijtmans, L., and Ostergard, E. (2013) A Patient with Complex I Deficiency Caused by a Novel ACAD9 Mutation Not Responding to Riboflavin Treatment. JIMD. Rep. [PM:23996478].
  68. Orr, A. L., Ashok, D., Sarantos, M. R., Shi, T., Hughes, R. E., and Brand, M. D. (2013) Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening. Free Radic. Biol. Med. 65C:1047-1059. [PM:23994103].
  69. Sala, G., Arosio, A., Stefanoni, G., Melchionda, L., Riva, C., Marinig, D., Brighina, L., and Ferrarese, C. (2013) Rotenone Upregulates Alpha-Synuclein and Myocyte Enhancer Factor 2D Independently from Lysosomal Degradation Inhibition. Biomed. Res. Int. 2013:846725- [PM:23984410].
  70. Birrell, J. A., Morina, K., Bridges, H. R., Friedrich, T., and Hirst, J. (2013) Investigating the function of [2Fe-2S] cluster N1a, the off-pathway cluster in complex I, by manipulating its reduction potential. Biochem. J. [PM:23980528].
  71. Gao, F., Chen, D., Hu, Q., and Wang, G. (2013) Rotenone Directly Induces BV2 Cell Activation via the p38 MAPK Pathway. PLoS. ONE. 8:e72046- [PM:23977201].
  72. Gauthier, L. D., Greenstein, J. L., Cortassa, S., O'Rourke, B., and Winslow, R. L. (2013) A computational model of reactive oxygen species and redox balance in cardiac mitochondria. Biophys. J. 105:1045-1056. [PM:23972856].
  73. Song, H., Liu, Y., Xiong, L., Li, Y., Yang, N., and Wang, Q. (2013) Design, Synthesis, and Insecticidal Evaluation of New Pyrazole Derivatives Containing Imine, Oxime Ether, Oxime Ester and Dihydro-isoxazoline Groups Based on the Inhibitor Binding Pocket of Respiratory Complex I. J. Agric. Food Chem. [PM:23972278].
  74. Villeneuve, L., Tiede-Lewis, L., Morsey, B., and Fox, H. (2013) Quantitative proteomics reveals oxygen-dependent changes in neuronal mitochondria affecting function and sensitivity to rotenone. J. Proteome. Res. [PM:23971408].
  75. Haorah, J., Rump, T. J., and Xiong, H. (2013) Reduction of Brain Mitochondrial beta-Oxidation Impairs Complex I and V in Chronic Alcohol Intake: The Underlying Mechanism for Neurodegeneration. PLoS. ONE. 8:e70833- [PM:23967116].
  76. Garcia-Nino, W. R., Tapia, E., Zazueta, C., Zatarain-Barron, Z. L., Hernandez-Pando, R., Vega-Garcia, C. C., and Pedraza-Chaverri, J. (2013) Curcumin pretreatment prevents potassium dichromate-induced hepatotoxicity, oxidative stress, decreased respiratory complex I activity, and membrane permeability transition pore opening. Evid. Based. Complement Alternat. Med. 2013:424692- [PM:23956771].
  77. Ma, Y. Y., Wu, T. F., Liu, Y. P., Wang, Q., Song, J. Q., Li, X. Y., Shi, X. Y., Zhang, W. N., Zhao, M., Hu, L. Y., Yang, Y. L., and Zou, L. P. (2013) Genetic and biochemical findings in Chinese children with Leigh syndrome. J. Clin. Neurosci. [PM:23953430].
  78. Venancio, C., Antunes, L., Felix, L., Rodrigues, P., Summavielle, T., and Peixoto, F. (2013) Chronic ketamine administration impairs mitochondrial complex I in the rat liver. Life Sci. [PM:23942268].
  79. Berndt, N., Holzhutter, H. G., and Bulik, S. (2013) Implications of enzyme deficiencies on the mitochondrial energy metabolism and ROS formation of neurons involved in rotenone-induced Parkinson's disease: A model-based analysis. FEBS J. [PM:23937586].
  80. Poliquin, P. O., Chen, J., Cloutier, M., Trudeau, L. E., and Jolicoeur, M. (2013) Metabolomics and in-silico analysis reveal critical energy deregulations in animal models of Parkinson's disease. PLoS. ONE. 8:e69146- [PM:23935941].
  81. Cappelli, E., Ravera, S., Vaccaro, D., Cuccarolo, P., Bartolucci, M., Panfoli, I., Dufour, C., and Degan, P. (2013) Mitochondrial respiratory complex I defects in Fanconi anemia. Trends Mol. Med. [PM:23932594].
  82. Karamanlidis, G., Lee, C. F., Garcia-Menendez, L., Kolwicz, S. C., Jr., Suthammarak, W., Gong, G., Sedensky, M. M., Morgan, P. G., Wang, W., and Tian, R. (2013) Mitochondrial complex I deficiency increases protein acetylation and accelerates heart failure. Cell Metab 18:239-250. [PM:23931755].
  83. Ma, J., Zhang, Q., Chen, S., Fang, B., Yang, Q., Chen, C., Miele, L., Sarkar, F. H., Xia, J., and Wang, Z. (2013) Mitochondrial Dysfunction Promotes Breast Cancer Cell Migration and Invasion through HIF1alpha Accumulation via Increased Production of Reactive Oxygen Species. PLoS. ONE. 8:e69485- [PM:23922721].
  84. Garcia-Ruiz, I., Solis-Munoz, P., Fernandez-Moreira, D., Munoz-Yague, T., and Solis-Herruzo, J. A. (2013) Pioglitazone leads to an inactivation and disassembly of complex I of the mitochondrial respiratory chain. BMC. Biol. 11:88- [PM:23915000].
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