Publications (2010)

1. Yusnita, Y., Norsiah, M. D., and Rahman, A. J. (2010) Mutations in mitochondrial NADH dehydrogenase subunit 1 (mtND1) gene in colorectal carcinoma. Malays. J. Pathol. 32:103-110. [PM:21329181].
2. Zhang, W., Chen, X., Gong, W., Tang, J., Tan, L., Guo, H., and Yao, Y. G. (2010) Common promoter variants of the NDUFV2 gene do not confer susceptibility to schizophrenia in Han Chinese. Behav. Brain Funct. 6:75- [PM:21190551].
3. Barber-Singh, J., Seo, B. B., Matsuno-Yagi, A., and Yagi, T. (2010) Protective Role of rAAV-NDI1, Serotype 5, in an Acute MPTP Mouse Parkinson's Model. Parkinsons. Dis. 2011:438370- [PM:21188192].
4. Dong, D. J., Liu, P. C., Wang, J. X., and Zhao, X. F. (2010) The knockdown of Ha-GRIM-19 by RNA interference induced programmed cell death. Amino. Acids [PM:21184119].
5. Klodmann, J. and Braun, H. P. (2010) Proteomic approach to characterize mitochondrial complex I from plants. Phytochemistry [PM:21167537].
6. Chen, S. D., Yw, C. A., and Chuang, Y. C. (2010) The potential role of mitochondrial dysfunction in seizure-associated cell death in the hippocampus and epileptogenesis. J. Bioenerg. Biomembr. 42:461-465. [PM:21153870].
7. Klusa, V. Z., Isajevs, S., Svirina, D., Pupure, J., Beitnere, U., Rumaks, J., Svirskis, S., Jansone, B., Dzirkale, Z., Muceniece, R., Kalvinsh, I., and Vinters, H. V. (2010) Neuroprotective properties of mildronate, a small molecule, in a rat model of Parkinson's disease. Int. J. Mol. Sci. 11:4465-4487. [PM:21151450].
8. Hielscher, R., Friedrich, T., and Hellwig, P. (2010) Far- and Mid-Infrared Spectroscopic Analysis of the Substrate-Induced Structural Dynamics of Respiratory Complex I. Chemphyschem. [PM:21140392].
9. Casutt, M. S., Wendelspiess, S., Steuber, J., and Fritz, G. (2010) Crystallization of the Na+-translocating NADH:quinone oxidoreductase from Vibrio cholerae. Acta Crystallogr. Sect. F. Struct. Biol. Cryst. Commun. 66:1677-1679. [PM:21139223].
10. Bathgate, D., Yu-Wai-Man, P., Webb, B., Taylor, R. W., Fowler, B., and Chinnery, P. F. (2010) Recessive spastic paraparesis associated with complex I deficiency due to MTHFR mutations. J. Neurol. Neurosurg. Psychiatry [PM:21131308].
11. Amarneh, B. and Vik, S. B. (2010) Transmembrane topology of subunit N of complex I (NADH:ubiquinone oxidoreductase) from Escherichia coli. J. Bioenerg. Biomembr. 42:511-516. [PM:21120593].
12. Vehovszky, A., Szabo, H., Acs, A., Gyori, J., and Farkas, A. (2010) Effects of rotenone and other mitochondrial complex I inhibitors on the brine shrimp Artemia. Acta Biol. Hung. 61:401-410. [PM:21112832].
13. Pan-Montojo, F. J. and Funk, R. H. (2010) Oral Administration of Rotenone using a Gavage and Image Analysis of Alpha-synuclein Inclusions in the Enteric Nervous System. J. Vis. Exp. 44: pii: 2123. [PM:21085094].
14. Bk, B., Bal, A., Kandimalla, R. J., and Gill, K. D. (2010) Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, alpha synuclein aggregation, oxidative damage and behavioral changes. Mol. Brain 3:35- [PM:21073741].
15. Chaves, R. S., Melo, T. Q., Martins, S. A., and Ferrari, M. F. (2010) Protein aggregation containing beta-amyloid, alpha-synuclein and hyperphosphorylated tau in cultured cells of hippocampus, substantia nigra and locus coeruleus after rotenone exposure. BMC. Neurosci. 11:144- [PM:21067569].
16. Sapkota, K., Kim, S., Park, S. E., and Kim, S. J. (2010) Detoxified Extract of Rhus verniciflua Stokes Inhibits Rotenone-Induced Apoptosis in Human Dopaminergic Cells, SH-SY5Y. Cell Mol. Neurobiol. [PM:21061154].
17. Haack, T. B., Danhauser, K., Haberberger, B., Hoser, J., Strecker, V., Boehm, D., Uziel, G., Lamantea, E., Invernizzi, F., Poulton, J., Rolinski, B., Iuso, A., Biskup, S., Schmidt, T., Mewes, H. W., Wittig, I., Meitinger, T., Zeviani, M., and Prokisch, H. (2010) Exome sequencing identifies ACAD9 mutations as a cause of complex I deficiency. Nat. Genet. 42:1131-1134. [PM:21057504].
18. Battchikova, N., Eisenhut, M., and Aro, E. M. (2010) Cyanobacterial NDH-1 complexes: Novel insights and remaining puzzles. Biochim. Biophys. Acta [PM:21035426].
19. Peng, L., Yamamoto, H., and Shikanai, T. (2010) Structure and biogenesis of the chloroplast NAD(P)H dehydrogenase complex. Biochim. Biophys. Acta [PM:21029720].
20. Castro-Guerrero, N., Sinha, P. K., Torres-Bacete, J., Matsuno-Yagi, A., and Yagi, T. (2010) Pivotal Roles of Three Conserved Carboxyl Residues of NuoC (30k) Segment in the Structural Integrity of Proton-translocating NADH-Quinone Oxidoreductase (NDH-1) from Escherichia coli. Biochemistry 49:10072-10080. [PM:20979355].
21. Hayashi, T. and Stuchebrukhov, A. A. (2010) Electron tunneling in respiratory complex I. Proc. Natl. Acad. Sci. U. S. A 107:19157-19162. [PM:20974925].
22. Suthammarak, W., Morgan, P. G., and Sedensky, M. M. (2010) Mutations in mitochondrial complex III uniquely affect complex I in Caenorhabditis elegans. J. Biol. Chem. 285:40724-40731. [PM:20971856].
23. Nishioka, K., Vilarino-Guell, C., Cobb, S. A., Kachergus, J. M., Ross, O. A., Hentati, E., Hentati, F., and Farrer, M. J. (2010) Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson disease. Parkinsonism. Relat Disord. 16:686-687. [PM:20971673].
24. Pohl, T., Spatzal, T., Aksoyoglu, M., Schleicher, E., Rostas, A. M., Lay, H., Glessner, U., Boudon, C., Hellwig, P., Weber, S., and Friedrich, T. (2010) Spin labeling of the Escherichia coli NADH ubiquinone oxidoreductase (complex I). Biochim. Biophys. Acta 1797:1894-1900. [PM:20959113].
25. Sakaue, Y., Kim, J., and Miyamoto, Y. (2010) Effects of TAT-conjugated platinum nanoparticles on lifespan of mitochondrial electron transport complex I-deficient Caenorhabditis elegans, nuo-1. Int. J. Nanomedicine. 5:687-695. [PM:20957220].
26. Moreira, E. L., Rial, D., Aguiar, A. S., Jr., Figueiredo, C. P., Siqueira, J. M., Dalbo, S., Horst, H., de, O. J., Mancini, G., Dos Santos, T. S., Villarinho, J. G., Pinheiro, F. V., Marino-Neto, J., Ferreira, J., De Bem, A. F., Latini, A., Pizzolatti, M. G., Ribeiro-do-Valle, R. M., and Prediger, R. D. (2010) Proanthocyanidin-rich fraction from Croton celtidifolius Baill confers neuroprotection in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine rat model of Parkinson's disease. J. Neural Transm. 117:1337-1351. [PM:20931248].
27. Ono, H., Nakamura, H., and Matsuzaki, M. (2010) A NADH dehydrogenase ubiquinone flavoprotein is decreased in patients with dilated cardiomyopathy. Intern. Med. 49:2039-2042. [PM:20930427].
28. Colborn, J. M., Kosoy, M. Y., Motin, V. L., Telepnev, M. V., Valbuena, G., Myint, K. S., Fofanov, Y., Putonti, C., Feng, C., and Peruski, L. (2010) Improved detection of Bartonella DNA in mammalian hosts and arthropod vectors using the NADH dehydrogenase gamma subunit (nuoG) by real-time PCR. J. Clin. Microbiol. 48:4630-4633. [PM:20926707].
29. Navarro, A. and Boveris, A. (2010) Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinson's disease. Front Aging Neurosci. 2: [PM:20890446].
30. Chinta, S. J., Mallajosyula, J. K., Rane, A., and Andersen, J. K. (2010) Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo. Neurosci. Lett. 486:235-239. [PM:20887775].
31. Navarro, A., Bandez, M. J., Gomez, C., Repetto, M. G., and Boveris, A. (2010) Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity. J. Bioenerg. Biomembr. 42:405-412. [PM:20886364].
32. Myers, C. R., Antholine, W. E., and Myers, J. M. (2010) The pro-oxidant chromium(VI) inhibits mitochondrial complex I, complex II, and aconitase in the bronchial epithelium: EPR markers for Fe-S proteins. Free Radic. Biol. Med. 49:1903-1915. [PM:20883776].
33. Gershoni, M., Fuchs, A., Shani, N., Fridman, Y., Corral-Debrinski, M., Aharoni, A., Frishman, D., and Mishmar, D. (2010) Co-evolution predicts direct interactions between mtDNA and nuclear DNA-encoded subunits of oxidative phosphorylation complex I. J. Mol. Biol. 404:158-171. [PM:20868692].
34. Fassone, E., Duncan, A. J., Taanman, J. W., Pagnamenta, A. T., Sadowski, M. I., Holand, T., Qasim, W., Rutland, P., Calvo, S. E., Mootha, V. K., Bitner-Glindzicz, M., and Rahman, S. (2010) FOXRED1, encoding a FAD-dependent oxidoreductase complex-I specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy. Hum. Mol. Genet. 19:4837-4847. [PM:20858599].
35. Hagopian, K., Weber, K. L., Hwee, D. T., Van Eenennaam, A. L., Lopez-Lluch, G., Villalba, J. M., Buron, I., Navas, P., German, J. B., Watkins, S. M., Chen, Y., Wei, A., McDonald, R. B., and Ramsey, J. J. (2010) Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice. PLoS. ONE. 5:e12696- [PM:20856881].
36. Birrell, J. A. and Hirst, J. (2010) Truncation of subunit ND2 disrupts the threefold symmetry of the antiporter-like subunits in complex I from higher metazoans. FEBS Lett. 584:4247-4252. [PM:20846527].
37. Lam, B. L., Feuer, W. J., Abukhalil, F., Porciatti, V., Hauswirth, W. W., and Guy, J. (2010) Leber hereditary optic neuropathy gene therapy clinical trial recruitment: year 1. Arch. Ophthalmol. 128:1129-1135. [PM:20837795].
38. Nakamaru-Ogiso, E., Kao, M. C., Chen, H., Sinha, S. C., Yagi, T., and Ohnishi, T. (2010) The membrane subunit NuoL(ND5) is involved in the indirect proton pumping mechanism of E. coli complex I. J. Biol. Chem. 285:39070-39078. [PM:20826797].
39. Tuppen, H. A., Hogan, V. E., He, L., Blakely, E. L., Worgan, L., Al-Dosary, M., Saretzki, G., Alston, C. L., Morris, A. A., Clarke, M., Jones, S., Devlin, A. M., Mansour, S., Chrzanowska-Lightowlers, Z. M., Thorburn, D. R., McFarland, R., and Taylor, R. W. (2010) The p.M292T NDUFS2 mutation causes complex I-deficient Leigh syndrome in multiple families. Brain 133:2952-2963. [PM:20819849].
40. Valsecchi, F., Koopman, W. J., Manjeri, G. R., Rodenburg, R. J., Smeitink, J. A., and Willems, P. H. (2010) Complex I disorders: causes, mechanisms, and development of treatment strategies at the cellular level. Dev. Disabil. Res. Rev. 16:175-182. [PM:20818732].
41. Calvo, S. E., Tucker, E. J., Compton, A. G., Kirby, D. M., Crawford, G., Burtt, N. P., Rivas, M., Guiducci, C., Bruno, D. L., Goldberger, O. A., Redman, M. C., Wiltshire, E., Wilson, C. J., Altshuler, D., Gabriel, S. B., Daly, M. J., Thorburn, D. R., and Mootha, V. K. (2010) High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency. Nat. Genet. 42:851-858. [PM:20818383].
42. Junyent, F., Alvira, D., Yeste-Velasco, M., de la Torre, A. V., Beas-Zarate, C., Sureda, F. X., Folch, J., Pallas, M., Camins, A., and Verdaguer, E. (2010) Prosurvival role of JAK/STAT and Akt signaling pathways in MPP+-induced apoptosis in neurons. Neurochem. Int. [PM:20817061].
43. Ohnishi, T., Nakamaru-Ogiso, E., and Ohnishi, S. T. (2010) A new hypothesis on the simultaneous direct and indirect proton pump mechanisms in NADH-quinone oxidoreductase (complex I). FEBS Lett. [PM:20816962].
44. Nouws, J., Nijtmans, L., Houten, S. M., van den Brand, M., Huynen, M., Venselaar, H., Hoefs, S., Gloerich, J., Kronick, J., Hutchin, T., Willems, P., Rodenburg, R., Wanders, R., Van den Heuvel, L., Smeitink, J., and Vogel, R. O. (2010) Acyl-CoA dehydrogenase 9 is required for the biogenesis of oxidative phosphorylation complex I. Cell Metab 12:283-294. [PM:20816094].
45. Scheffler, I. E. (2010) Assembling complex I with ACAD9. Cell Metab 12:211-212. [PM:20816087].
46. Chen, X., Qi, F., Dash, R. K., and Beard, D. A. (2010) Kinetics and regulation of mammalian NADH-ubiquinone oxidoreductase (Complex I). Biophys. J. 99:1426-1436. [PM:20816054].
47. Chinta, S. J. and Andersen, J. K. (2010) Nitrosylation and nitration of mitochondrial complex I in Parkinson's disease. Free Radic. Res. [PM:20815786].
48. Wu, C., Yang, K., Liu, Q., Wakui, M., Jin, G. Z., Zhen, X., and Wu, J. (2010) Tetrahydroberberine blocks ATP-sensitive potassium channels in dopamine neurons acutely-dissociated from rat substantia nigra pars compacta. Neuropharmacology [PM:20804776].
49. Pagniez-Mammeri, H., Landrieu, P., Legrand, A., and Slama, A. (2010) Leukoencephalopathy with vanishing white matter caused by compound heterozygous mutations in mitochondrial complex I NDUFS1 subunit. Mol. Genet. Metab [PM:20797884].
50. Lomba, A., Martinez, J. A., Garcia-Diaz, D. F., Paternain, L., Marti, A., Campion, J., and Milagro, F. I. (2010) Weight gain induced by an isocaloric pair-fed high fat diet: A nutriepigenetic study on FASN and NDUFB6 gene promoters. Mol. Genet. Metab [PM:20729114].
51. van den Ecker, D., van den Brand, M. A., Bossinger, O., Mayatepek, E., Nijtmans, L. G., and Distelmaier, F. (2010) Blue native electrophoresis to study mitochondrial complex I in C. elegans. Anal. Biochem. [PM:20705045].
52. Gupta, A., Kumar, A., and Kulkarni, S. K. (2010) Licofelone attenuates MPTP-induced neuronal toxicity: behavioral, biochemical and cellular evidence. Inflammopharmacology. [PM:20697819].
53. Perier, C., Bove, J., Dehay, B., Jackson-Lewis, V., Rabinovitch, P. S., Przedborski, S., and Vila, M. (2010) Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins. Ann. Neurol. 68:184-192. [PM:20695011].
54. Batista, A. P., Franco, C., Mendes, M., Coelho, A. V., and Pereira, M. M. (2010) Subunit composition of Rhodothermus marinus respiratory complex I. Anal. Biochem. [PM:20692224].
55. Sengupta, T. and Mohanakumar, K. P. (2010) 2-Phenylethylamine, a constituent of chocolate and wine, causes mitochondrial complex-I inhibition, generation of hydroxyl radicals and depletion of striatal biogenic amines leading to psycho-motor dysfunctions in Balb/c mice. Neurochem. Int. [PM:20691235].
56. Zhang, J., Zhou, X., Zhou, J., Li, C., Zhao, F., Wang, Y., Meng, Y., Wang, J., Yuan, M., Cai, W., Tong, Y., Sun, Y. H., Yang, L., Qu, J., and Guan, M. X. (2010) Mitochondrial ND6 T14502C variant may modulate the phenotypic expression of LHON-associated G11778A mutation in four Chinese families. Biochem. Biophys. Res. Commun. [PM:20691156].
57. Lefort, N., Glancy, B., Bowen, B., Willis, W. T., Bailowitz, Z., De Filippis, E. A., Brophy, C., Meyer, C., Hojlund, K., Yi, Z., and Mandarino, L. J. (2010) Increased ROS production and lower abundance of complex I subunits and carnitine palmitoyltransferase 1B protein despite normal mitochondrial respiration in insulin resistant human skeletal muscle. Diabetes [PM:20682693].
58. Yokota, M., Shitara, H., Hashizume, O., Ishikawa, K., Nakada, K., Ishii, R., Taya, C., Takenaga, K., Yonekawa, H., and Hayashi, J. I. (2010) Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells. FEBS Lett. [PM:20674568].
59. Wang, Y., Gulis, G., Buckner, S., Johnson, P. C., Sullivan, D., Busenlehner, L., and Marcus, S. (2010) The MAP Kinase Pmk1 and Protein Kinase A Are Required for Rotenone Resistance in the Fission Yeast, Schizosaccharomyces pombe. Biochem. Biophys. Res. Commun. [PM:20655879].
60. Dinamarco, T. M., de Castro, P. B., Savoldi, M., Malavazi, I., Soriani, F. M., Uyemura, S. A., Ludovico, P., Goldman, M. H., and Goldman, G. H. (2010) The roles played by Aspergillus nidulans Apoptosis Inducing Factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance. Fungal. Genet. Biol. [PM:20654725].
61. Tripathy, M. K., Ahmed, Z., Ladha, J. S., and Mitra, D. (2010) The cell death regulator GRIM-19 is involved in HIV-1 induced T-cell apoptosis. Apoptosis. [PM:20640890].
62. Morgan, J. B., Mahdi, F., Liu, Y., Coothankandaswamy, V., Jekabsons, M. B., Johnson, T. A., Sashidhara, K. V., Crews, P., Nagle, D. G., and Zhou, Y. D. (2010) The marine sponge metabolite mycothiazole: A novel prototype mitochondrial complex I inhibitor. Bioorg. Med. Chem. [PM:20637638].
63. Albracht, S. P. (2010) The reaction of NADPH with bovine mitochondrial NADH:ubiquinone oxidoreductase revisited : II. Comparison of the proposed working hypothesis with literature data. J. Bioenerg. Biomembr. [PM:20632077].
64. Albracht, S. P. (2010) The reaction of NADPH with bovine mitochondrial NADH:ubiquinone oxidoreductase revisited : I. Proposed consequences for electron transfer in the enzyme. J. Bioenerg. Biomembr. [PM:20628895].
65. Marella, M., Seo, B. B., Thomas, B. B., Matsuno-Yagi, A., and Yagi, T. (2010) Successful amelioration of mitochondrial optic neuropathy using the yeast NDI1 gene in a rat animal model. PLoS. ONE. 5:e11472- [PM:20628600].
66. Koilkonda, R. D., Chou, T. H., Porciatti, V., Hauswirth, W. W., and Guy, J. (2010) Induction of rapid and highly efficient expression of the human ND4 complex I subunit in the mouse visual system by self-complementary adeno-associated virus. Arch. Ophthalmol. 128:876-883. [PM:20625049].
67. Khan, S., Nanduri, J., Yuan, G., Kinsman, B., Kumar, G. K., Joseph, J., Kalyanaraman, B., and Prabhakar, N. R. (2010) NOX2 MEDIATES INTERMITTENT HYPOXIA-INDUCED MITOCHONDRIAL COMPLEX I INHIBITION: RELEVANCE TO BLOOD PRESSURE CHANGES IN RATS. Antioxid. Redox. Signal. [PM:20618070].
68. Juarez, O., Morgan, J. E., Nilges, M. J., and Barquera, B. (2010) Energy transducing redox steps of the Na+-pumping NADH:quinone oxidoreductase from Vibrio cholerae. Proc. Natl. Acad. Sci. U. S. A 107:12505-12510. [PM:20616050].
69. Bridges, H. R., Fearnley, I. M., and Hirst, J. (2010) The subunit composition of mitochondrial NADH:ubiquinone oxidoreductase (complex I) from Pichia pastoris. Mol. Cell Proteomics. [PM:20610779].
70. Rio, M., Lebre, A. S., de, L. P., Valayannopoulos, V., Desguerre, I., Dufier, J. L., Grevent, D., Zilbovicius, M., Treguier, C., Brunelle, F., de, B. C., Kaplan, J., Espinase-Berrod, M. A., Sainte-Rose, C., Puget, S., Rotig, A., Munnich, A., and Boddaert, N. (2010) Mitochondrial ND5 mutations mimicking brainstem tectal glioma. Neurology 75:93- [PM:20603491].
71. Ohnishi, S. T., Salerno, J. C., and Ohnishi, T. (2010) Possible roles of two quinone molecules in direct and indirect proton pumps of bovine heart NADH-quinone oxidoreductase (complex I). Biochim. Biophys. Acta [PM:20599678].
72. Lu, L., Gu, L., Liang, Y., Sun, X., Duan, C., and Yang, H. (2010) Dual effects of alpha-synuclein on neurotoxicity induced by low dosage of rotenone are dependent on exposure time in dopaminergic neuroblastoma cells. Sci. China Life Sci. 53:590-597. [PM:20596942].
73. Hunte, C., Zickermann, V., and Brandt, U. (2010) Functional modules and structural basis of conformational coupling in mitochondrial complex I. Science 329:448-451. [PM:20595580].
74. Herzer, M., Koch, J., Prokisch, H., Rodenburg, R., Rauscher, C., Radauer, W., Forstner, R., Pilz, P., Rolinski, B., Freisinger, P., Mayr, J. A., and Sperl, W. (2010) Leigh disease with brainstem involvement in complex I deficiency due to assembly factor NDUFAF2 defect. Neuropediatrics 41:30-34. [PM:20571988].
75. Kang, P. T., Yun, J., Kaumaya, P. P., and Chen, Y. R. (2010) Design and use of peptide-based antibodies decreasing superoxide production by mitochondrial complex I and complex II. Biopolymers [PM:20564035].
76. Lomba, A., Milagro, F. I., Garcia-Diaz, D. F., Campion, J., Marzo, F., and Martinez, J. A. (2010) A High-Sucrose Isocaloric Pair-Fed Model Induces Obesity and Impairs NDUFB6 Gene Function in Rat Adipose Tissue. J. Nutrigenet. Nutrigenomics. 2:267-272. [PM:20559011].
77. Casutt, M. S., Huber, T., Brunisholz, R., Tao, M., Fritz, G., and Steuber, J. (2010) Localization and function of the membrane-bound riboflavin in the Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) from Vibrio cholerae. J. Biol. Chem. [PM:20558724].
78. McKenzie, M. and Ryan, M. T. (2010) Assembly factors of human mitochondrial complex I and their defects in disease. IUBMB. Life 62:497-502. [PM:20552642].
79. Shen, L., Wei, J., Chen, T., He, J., Qu, J., He, X., Jiang, L., Qu, Y., Fang, H., Chen, G., Lu, J., and Bai, Y. (2010) Evaluating mitochondrial DNA in patients with breast cancer and benign breast disease. J. Cancer Res. Clin. Oncol. [PM:20552226].
80. Wu, H., Xing, K., and Lou, M. F. (2010) Glutaredoxin 2 prevents H2O2-induced cell apoptosis by protecting complex I activity in the mitochondria. Biochim. Biophys. Acta [PM:20547138].
81. Wu, Y., Li, X., Xie, W., Jankovic, J., Le, W., and Pan, T. (2010) Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1alpha and induction of autophagy in SH-SY5Y cells. Neurochem. Int. [PM:20546814].
82. Gawryluk, R. M. and Gray, M. W. (2010) Evidence for an early evolutionary emergence of gamma-type carbonic anhydrases as components of mitochondrial respiratory complex I. BMC. Evol. Biol. 10:176- [PM:20546574].
83. Lieberman, J. (2010) Granzyme A activates another way to die. Immunol. Rev. 235:93-104. [PM:20536557].
84. Quintana, A., Kruse, S. E., Kapur, R. P., Sanz, E., and Palmiter, R. D. (2010) Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome. Proc. Natl. Acad. Sci. U. S. A 107:10996-11001. [PM:20534480].
85. Steffen, W., Gemperli, A. C., Cvetesic, N., and Steuber, J. (2010) Organelle-specific expression of subunit ND5 of human complex I (NADH dehydrogenase) alters cation homeostasis in Saccharomyces cerevisiae. FEMS Yeast Res. [PM:20528953].
86. Prochazka, E., Polakova, S., Piskur, J., and Sulo, P. (2010) Mitochondrial genome from the facultative anaerobe and petite-positive yeast Dekkera bruxellensis contains the NADH dehydrogenase subunit genes. FEMS Yeast Res. [PM:20528950].
87. Finsterer, J. (2010) Mitochondrial disorder mimicking ocular myasthenia. Acta Neurol. Belg. 110:110-112. [PM:20514938].
88. Passarelli, C., Tozzi, G., Pastore, A., Bertini, E., and Piemonte, F. (2010) GSSG-mediated Complex I defect in isolated cardiac mitochondria. Int. J. Mol. Med. 26:95-99. [PM:20514427].
89. Kirches, E. (2009) Do mtDNA Mutations Participate in the Pathogenesis of Sporadic Parkinson's Disease? Curr. Genomics 10:585-593. [PM:20514220].
90. Ohnishi, S. T., Shinzawa-Itoh, K., Ohta, K., Yoshikawa, S., and Ohnishi, T. (2010) New insights into the superoxide generation sites in bovine heart NADH-ubiquinone oxidoreductase (Complex I): The significance of protein-associated ubiquinone and the dynamic shifting of generation sites between semiflavin and semiquinone radicals. Biochim. Biophys. Acta [PM:20513438].
91. Medvedev, E. S., Couch, V. A., and Stuchebrukhov, A. A. (2010) Determination of the intrinsic redox potentials of FeS centers of respiratory complex I from experimental titration curves. Biochim. Biophys. Acta [PM:20513348].
92. Liu, W. B., Zhou, J., Qu, Y., Li, X., Lu, C. T., Xie, K. L., Sun, X. L., and Fei, Z. (2010) Neuroprotective effect of osthole on MPP+-induced cytotoxicity in PC12 cells via inhibition of mitochondrial dysfunction and ROS production. Neurochem. Int. [PM:20510317].
93. Gustavsson, T., Trane, M., Moparthi, V. K., Miklovyte, E., Moparthi, L., Gorecki, K., Leiding, T., Arskold, S. P., and Hagerhall, C. (2010) A cytochrome c- fusion protein domain for convenient detection, quantification and enhanced production of membrane proteins in Escherichia coli - expression and characterization of cytochrome-tagged complex I subunits. Protein Sci. [PM:20509166].
94. Efremov, R. G., Baradaran, R., and Sazanov, L. A. (2010) The architecture of respiratory complex I. Nature 465:441-445. [PM:20505720].
95. He, X. and Cao, X. (2010) Identification of alternatively spliced GRIM-19 mRNA in kidney cancer tissues. J. Hum. Genet. [PM:20505682].
96. Yeh, S. T., Angelos, M. G., and Chen, Y. R. (2010) Simplified method for concentration of mitochondrial membrane protein complexes. Electrophoresis [PM:20503203].
97. Hadzsiev, K., Maasz, A., Kisfali, P., Kalman, E., Gomori, E., Pal, E., Berenyi, E., Komlosi, K., and Melegh, B. (2010) Mitochondrial DNA 11777C>A Mutation Associated Leigh Syndrome: Case Report with a Review of the Previously Described Pedigrees. Neuromolecular. Med. [PM:20502985].
98. Tocilescu, M. A., Zickermann, V., Zwicker, K., and Brandt, U. (2010) Quinone binding and reduction by respiratory complex I. Biochim. Biophys. Acta [PM:20493164].
99. Cao, Y., Jin, N., Xu, H., Liu, Y., Zhu, W. H., Li, X. R., Qiao, D. R., and Cao, Y. (2010) Characterization and alternative splicing of the complex I 19-kD subunit in Dunaliella salina: expression and mutual correlation of splice variants under diverse stresses. Biosci. Biotechnol. Biochem. 74:1073-1078. [PM:20460714].
100. Kakutani, N., Murai, M., Sakiyama, N., and Miyoshi, H. (2010) Exploring the Binding Site of Deltalac-Acetogenin in Bovine Heart Mitochondrial NADH-Ubiquinone Oxidoreductase. Biochemistry [PM:20459120].
101. Leiris, S. J., Khdour, O. M., Segerman, Z. J., Tsosie, K. S., Chapuis, J. C., and Hecht, S. M. (2010) Synthesis and evaluation of verticipyrone analogues as mitochondrial complex I inhibitors. Bioorg. Med. Chem. 18:3481-3493. [PM:20456960].
102. Kumar, M., Tanwar, M., Saxena, R., Sharma, P., and Dada, R. (2010) Identification of novel mitochondrial mutations in Leber's hereditary optic neuropathy. Mol. Vis. 16:782-792. [PM:20454697].
103. Sanz, A., Soikkeli, M., Portero-Otin, M., Wilson, A., Kemppainen, E., McIlroy, G., Ellila, S., Kemppainen, K. K., Tuomela, T., Lakanmaa, M., Kiviranta, E., Stefanatos, R., Dufour, E., Hutz, B., Naudi, A., Jove, M., Zeb, A., Vartiainen, S., Matsuno-Yagi, A., Yagi, T., Rustin, P., Pamplona, R., and Jacobs, H. T. (2010) Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction. Proc. Natl. Acad. Sci. U. S. A 107:9105-9110. [PM:20435911].
104. Castro, A., Lemos, C., Falcao, A., Fernandes, A. S., Glass, N. L., and Videira, A. (2010) Rotenone enhances the antifungal properties of staurosporine. Eukaryot. Cell [PM:20435699].
105. Rasmo, D. D., Palmisano, G., Scacco, S., Technikova-Dobrova, Z., Panelli, D., Cocco, T., Sardanelli, A. M., Gnoni, A., Micelli, L., Trani, A., Luccia, A. D., and Papa, S. (2010) Phosphorylation pattern of the NDUFS4 subunit of complex I of the mammalian respiratory chain. Mitochondrion. [PM:20433953].
106. Puerta, E., Hervias, I., Goni-Allo, B., Zhang, S. F., Jordan, J., Starkov, A. A., and Aguirre, N. (2010) Methylenedioxymethamphetamine inhibits mitochondrial complex I activity in mice: a possible mechanism underlying neurotoxicity. Br. J. Pharmacol. 160:233-245. [PM:20423338].
107. Poeggeler, B., Sambamurti, K., Siedlak, S. L., Perry, G., Smith, M. A., and Pappolla, M. A. (2010) A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan. PLoS. ONE. 5:e10206- [PM:20421998].
108. Miller, J. L., Velmurugan, K., Cowan, M. J., and Briken, V. (2010) The type I NADH dehydrogenase of Mycobacterium tuberculosis counters phagosomal NOX2 activity to inhibit TNF-alpha-mediated host cell apoptosis. PLoS. Pathog. 6:e1000864- [PM:20421951].
109. Alvarez, C. O., Salvatore, A., Willink, E., Ordonez, R., Isla, M. I., Neske, A., and Bardon, A. (2010) Insecticidal, mutagenic and genotoxic evaluation of annonaceous acetogenins. Nat. Prod. Commun. 5:391-394. [PM:20420314].
110. Chou, A. P., Li, S., Fitzmaurice, A. G., and Bronstein, J. M. (2010) Mechanisms of Rotenone-induced Proteasome Inhibition. Neurotoxicology [PM:20417232].
111. Pei, Z., Gustavsson, T., Roth, R., Frejd, T., and Hagerhall, C. (2010) Photolabile ubiquinone analogues for identification and characterization of quinone binding sites in proteins. Bioorg. Med. Chem. [PM:20409720].
112. Carilla-Latorre, S., Gallardo, M. E., Annesley, S. J., Calvo-Garrido, J., Grana, O., Accari, S. L., Smith, P. K., Valencia, A., Garesse, R., Fisher, P. R., and Escalante, R. (2010) MidA is a putative methyltransferase that is required for mitochondrial complex I function. J. Cell Sci. [PM:20406883].
113. Maas, M. F., Sellem, C. H., Krause, F., Dencher, N. A., and Sainsard-Chanet, A. (2010) Molecular Gene Therapy: Overexpression of the Alternative NADH Dehydrogenase NDI1 Restores Overall Physiology in a Fungal Model of Respiratory Complex I Deficiency. J. Mol. Biol. [PM:20398675].
114. Perales-Clemente, E., Fernandez-Vizarra, E., Acin-Perez, R., Movilla, N., Bayona-Bafaluy, M. P., Moreno-Loshuertos, R., Perez-Martos, A., Fernandez-Silva, P., and Enriquez, J. A. (2010) Five Entry Points of the Mitochondrially Encoded Subunits in Mammalian Complex I Assembly. Mol. Cell Biol. [PM:20385768].
115. Hoefs, S. J., Skjeldal, O. H., Rodenburg, R. J., Nedregaard, B., van Kaauwen, E. P., Spiekerkotter, U., von Kleist-Retzow, J. C., Smeitink, J. A., Nijtmans, L. G., and Van den Heuvel, L. P. (2010) Novel mutations in the NDUFS1 gene cause low residual activities in human complex I deficiencies. Mol. Genet. Metab [PM:20382551].
116. Garbian, Y., Ovadia, O., Dadon, S., and Mishmar, D. (2010) Gene expression patterns of oxidative phosphorylation complex I subunits are organized in clusters. PLoS. ONE. 5:e9985- [PM:20376309].
117. Chomova, M. and Racay, P. (2010) Mitochondrial complex I in the network of known and unknown facts. Gen. Physiol Biophys. 29:3-11. [PM:20371875].
118. Andreazza, A. C., Shao, L., Wang, J. F., and Young, L. T. (2010) Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder. Arch. Gen. Psychiatry 67:360-368. [PM:20368511].
119. Schapira, A. H. (2010) Complex I: Inhibitors, inhibition and neurodegeneration. Exp. Neurol. [PM:20362572].
120. Fahnehjelm, K. T., Olsson, M., Naess, K., Wiberg, M., Ygge, J., Martin, L., and von, D. U. (2010) Visual function, ocular motility and ocular characteristics in patients with mitochondrial complex I deficiency. Acta Ophthalmol. [PM:20346082].
121. Yang, W. and Hekimi, S. (2010) Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans. Aging Cell [PM:20346072].
122. Kaminski, M. M., Sauer, S. W., Klemke, C. D., Suss, D., Okun, J. G., Krammer, P. H., and Gulow, K. (2010) Mitochondrial Reactive Oxygen Species Control T Cell Activation by Regulating IL-2 and IL-4 Expression: Mechanism of Ciprofloxacin-Mediated Immunosuppression. J. Immunol. [PM:20335530].
123. Greene, J. G., Dingledine, R., and Greenamyre, J. T. (2010) Neuron-selective changes in RNA transcripts related to energy metabolism in toxic models of parkinsonism in rodents. Neurobiol. Dis. [PM:20307667].
124. Papa, S., Scacco, S., De, R. D., Signorile, A., Papa, F., Panelli, D., Nicastro, A., Scaringi, R., Santeramo, A., Roca, E., Trentadue, R., and Larizza, M. (2010) cAMP-dependent protein kinase regulates post-translational processing and expression of complex I subunits in mammalian cells. Biochim. Biophys. Acta [PM:20303927].
125. Sanz, A., Stefanatos, R., and McIlroy, G. (2010) Production of reactive oxygen species by the mitochondrial electron transport chain in Drosophila melanogaster. J. Bioenerg. Biomembr. [PM:20300811].
126. Ransac, S., Arnarez, C., and Mazat, J. P. (2010) The flitting of electrons in complex I: A stochastic approach. Biochim. Biophys. Acta [PM:20230777].
127. Garcia-Ruiz, I., Fernandez-Moreira, D., Solis-Munoz, P., Rodriguez-Juan, C., Diaz-Sanjuan, T., Munoz-Yague, T., and Solis-Herruzo, J. A. (2010) Mitochondrial Complex I Subunits Are Decreased in Murine Nonalcoholic Fatty Liver Disease: Implication of Peroxynitrite. J. Proteome. Res. [PM:20222668].
128. Friedrich, T. and Hellwig, P. (2010) Redox-induced conformational changes within the Escherichia coli NADH ubiquinone oxidoreductase (complex I): An analysis by mutagenesis and FT-IR spectroscopy. Biochim. Biophys. Acta [PM:20214873].
129. Tonska, K., Kodron, A., and Bartnik, E. (2010) Genotype-phenotype correlations in Leber hereditary optic neuropathy. Biochim. Biophys. Acta [PM:20211598].
130. Abdulwahid, A., I and Ahmad, K. H. (2010) Environmental toxins and Parkinson's disease: putative roles of impaired electron transport chain and oxidative stress. Toxicol. Ind. Health 26:121-128. [PM:20207656].
131. Leshinsky-Silver, E., Lev, D., Malinger, G., Shapira, D., Cohen, S., Lerman-Sagie, T., and Saada, A. (2010) Leigh disease presenting in utero due to a novel missense mutation in the mitochondrial DNA-ND3. Mol. Genet. Metab [PM:20202874].
132. Arduino, D. M., Esteves, A. R., Oliveira, C. R., and Cardoso, S. M. (2010) Mitochondrial metabolism modulation: a new therapeutic approach for Parkinson's disease. CNS. Neurol. Disord. Drug Targets. 9:105-119. [PM:20201821].
133. Ning, T., Xiao, H., Li, J., Hua, S., and Zhang, Y. P. (2010) Adaptive evolution of the mitochondrial ND6 gene in the domestic horse. Genet. Mol. Res. 9:144-150. [PM:20198570].
134. Klodmann, J., Sunderhaus, S., Nimtz, M., Jansch, L., and Braun, H. P. (2010) Internal Architecture of Mitochondrial Complex I from Arabidopsis thaliana. Plant Cell [PM:20197505].
135. Hinttala, R., Kervinen, M., Uusimaa, J., Maliniemi, P., Finnila, S., Rantala, H., Remes, A. M., Hassinen, I. E., and Majamaa, K. (2010) Analysis of functional consequences of haplogroup J polymorphisms m.4216T>C and m.3866T>C in human MT-ND1: Mutagenesis of homologous positions in Escherichia coli. Mitochondrion. [PM:20197120].
136. Murai, M., Yamashita, T., Senoh, M., Mashimo, Y., Kataoka, M., Kosaka, H., Matsuno-Yagi, A., Yagi, T., and Miyoshi, H. (2010) Characterization of the Ubiquinone Binding Site in the Alternative NADH-Quinone Oxidoreductase of Saccharomyces cerevisiae by Photoaffinity Labeling. Biochemistry 49:2973-2980. [PM:20192260].
137. Grivennikova, V. G., Kareyeva, A. V., and Vinogradov, A. D. (2010) What are the sources of hydrogen peroxide production by heart mitochondria? Biochim. Biophys. Acta [PM:20170624].
138. Moran, M., Rivera, H., Sanchez-Arago, M., Blazquez, A., Merinero, B., Ugalde, C., Arenas, J., Cuezva, J. M., and Martin, M. A. (2010) Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts. Biochim. Biophys. Acta [PM:20153825].
139. Requejo, R., Hurd, T. R., Costa, N. J., and Murphy, M. P. (2010) Cysteine residues exposed on protein surfaces are the dominant intramitochondrial thiol and may protect against oxidative damage. FEBS J. [PM:20148960].
140. Corona, J. C., Gimenez-Cassina, A., Lim, F., and Diaz-Nido, J. (2010) Hexokinase II gene transfer protects against neurodegeneration in the rotenone and MPTP mouse models of Parkinson's disease. J. Neurosci. Res. [PM:20143419].
141. Hangen, E., Blomgren, K., Benit, P., Kroemer, G., and Modjtahedi, N. (2010) Life with or without AIF. Trends Biochem. Sci. [PM:20138767].
142. Roessler, M. M., King, M. S., Robinson, A. J., Armstrong, F. A., Harmer, J., and Hirst, J. (2010) Direct assignment of EPR spectra to structurally defined iron-sulfur clusters in complex I by double electron-electron resonance. Proc. Natl. Acad. Sci. U. S. A 107:1930-1935. [PM:20133838].
143. Raquel, E. A., Lu, J., Rodova, M., Onyango, I., Lezi, E., Dubinsky, R., Lyons, K. E., Pahwa, R., Burns, J. M., Cardoso, S. M., and Swerdlow, R. H. (2010) Mitochondrial Respiration and Respiration Associated Proteins in Cell Lines Created through Parkinson's Subject Mitochondrial Transfer. J. Neurochem. [PM:20132468].
144. Sokolova, L., Wittig, I., Barth, H. D., Schagger, H., Brutschy, B., and Brandt, U. (2010) LILBID-mass spectrometry of protein complexes from blue-native gels, a sensitive top-down proteomic approach. Proteomics. [PM:20127694].
145. Rigoulet, M., Mourier, A., Galinier, A., Casteilla, L., and Devin, A. (2010) Electron competition process in respiratory chain: Regulatory mechanisms and physiological functions. Biochim. Biophys. Acta [PM:20117078].
146. Tocilescu, M. A., Fendel, U., Zwicker, K., Drose, S., Kerscher, S., and Brandt, U. (2010) The role of a conserved tyrosine in the 49-kDa subunit of complex I for ubiquinone binding and reduction. Biochim. Biophys. Acta [PM:20117074].
147. Lenaz, G., Baracca, A., Barbero, G., Bergamini, C., Dalmonte, M. E., Del, S. M., Faccioli, M., Falasca, A., Fato, R., Genova, M. L., Sgarbi, G., and Solaini, G. (2010) Mitochondrial respiratory chain super-complex I-III in physiology and pathology. Biochim. Biophys. Acta [PM:20116362].
148. Koene, S., Willems, P. H., Roestenberg, P., Koopman, W. J., and Smeitink, J. A. (2010) Mouse models for nuclear DNA-encoded mitochondrial complex I deficiency. J. Inherit. Metab Dis. [PM:20107904].
149. Zhuang, X. and Cheng, C. H. (2010) ND6 gene "lost" and found: evolution of mitochondrial gene rearrangement in Antarctic notothenioids. Mol. Biol. Evol. [PM:20106908].
150. Batista, A. P., Fernandes, A. S., Louro, R. O., Steuber, J., and Pereira, M. M. (2010) Energy conservation by Rhodothermus marinus respiratory complex I. Biochim. Biophys. Acta [PM:20100453].
151. Pan-Montojo, F., Anichtchik, O., Dening, Y., Knels, L., Pursche, S., Jung, R., Jackson, S., Gille, G., Spillantini, M. G., Reichmann, H., and Funk, R. H. (2010) Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice. PLoS. ONE. 5:e8762- [PM:20098733].
152. Bahadorani, S., Cho, J., Lo, J. T., Contreras, H., Lawal, H. O., Krantz, D. E., Bradley, T. J., and Walker, D. W. (2010) Neuronal expression of a single-subunit yeast NADH-ubiquinone oxidoreductase (Ndi1) extends Drosophila lifespan. Aging Cell [PM:20089120].
153. Schonfeld, P., Wieckowski, M. R., Lebiedzinska, M., and Wojtczak, L. (2010) Mitochondrial fatty acid oxidation and oxidative stress: Lack of reverse electron transfer-associated production of reactive oxygen species. Biochim. Biophys. Acta [PM:20085746].
154. Telford, J. E., Kilbride, S. M., and Davey, G. P. (2010) Decylubiquinone increases mitochondrial function in synaptosomes. J. Biol. Chem. [PM:20080966].
155. Nakamaru-Ogiso, E., Han, H., Matsuno-Yagi, A., Keinan, E., Sinha, S. C., Yagi, T., and Ohnishi, T. (2010) The ND2 subunit was labeled by a photoaffinity analogue of asimicin, a potent complex I inhibitor. FEBS Lett. 584:883-888. [PM:20074573].
156. Geldenhuys, W. J., Funk, M. O., Barnes, K. F., and Carroll, R. T. (2010) Structure-based design of a thiazolidinedione which targets the mitochondrial protein mitoNEET. Bioorg. Med. Chem. Lett. 20:819-823. [PM:20064719].
157. Brand, M. D. (2010) The sites and topology of mitochondrial superoxide production. Exp. Gerontol. [PM:20064600].
158. Verkhovsky, M. I. and Bogachev, A. V. (2010) Sodium-translocating NADH:quinone oxidoreductase as a redox-driven ion pump. Biochim. Biophys. Acta [PM:20056102].
159. Loeb, V., Yakunin, E., Saada, A., and Sharon, R. (2010) The transgenic over expression of a-Synuclein and not its related pathology, associates with complex I inhibition. J. Biol. Chem. [PM:20053987].
160. Czarnecka, A. M., Klemba, A., Krawczyk, T., Zdrozny, M., Arnold, R. S., Bartnik, E., and Petros, J. A. (2010) Mitochondrial NADH-dehydrogenase polymorphisms as sporadic breast cancer risk factor. Oncol. Rep. 23:531-535. [PM:20043118].
161. Hirst, J. (2010) Towards the molecular mechanism of respiratory complex I. Biochem. J. 425:327-339. [PM:20025615].
162. Dermaut, B., Seneca, S., Dom, L., Smets, K., Ceulemans, L., Smet, J., De, P. B., Tousseyn, S., Weckhuysen, S., Gewillig, M., Pals, P., Parizel, P., De Bleecker, J. L., Boon, P., De, M. L., De, J. P., Van, C. R., Van, P. W., and Santens, P. (2010) Progressive myoclonic epilepsy as an adult-onset manifestation of Leigh syndrome due to m.14487T>C. J. Neurol. Neurosurg. Psychiatry 81:90-93. [PM:20019223].
163. Pupure, J., Isajevs, S., Skapare, E., Rumaks, J., Svirskis, S., Svirina, D., Kalvinsh, I., and Klusa, V. (2010) Neuroprotective properties of mildronate, a mitochondria-targeted small molecule. Neurosci. Lett. 470:100-105. [PM:20036318].
164. Porcelli, A. M., Ghelli, A., Ceccarelli, C., Lang, M., Cenacchi, G., Capristo, M., Pennisi, F., Morra, I., Ciccarelli, E., Melcarne, A., Bartoletti-Stella, A., Salfi, N., Tallini, G., Martinuzzi, A., Carelli, V., Attimonelli, M., Rugolo, M., Romeo, G., and Gasparre, G. (2010) The genetic and metabolic signature of oncocytic transformation implicates HIF1{alpha} destabilization. Hum. Mol. Genet. [PM:20028790].
165. Alston, C. L., Morak, M., Reid, C., Hargreaves, I. P., Pope, S. A., Land, J. M., Heales, S. J., Horvath, R., Mundy, H., and Taylor, R. W. (2010) A novel mitochondrial MTND5 frameshift mutation causing isolated complex I deficiency, renal failure and myopathy. Neuromuscul. Disord. 20:131-135. [PM:20018511].
166. Lambert, A. J., Buckingham, J. A., Boysen, H. M., and Brand, M. D. (2010) Low complex I content explains the low hydrogen peroxide production rate of heart mitochondria from the long-lived pigeon, Columba livia. Aging Cell 9:78-91. [PM:19968628].
167. Shinzawa-Itoh, K., Seiyama, J., Terada, H., Nakatsubo, R., Naoki, K., Nakashima, Y., and Yoshikawa, S. (2010) Bovine Heart NADH-Ubiquinone Oxidoreductase Contains One Molecule of Ubiquinone with Ten Isoprene Units as One of the Cofactors. Biochemistry 49:487-492. [PM:19961238].
168. Price, C. E. and Driessen, A. J. (2010) Conserved negative charges in the transmembrane segments of subunit K of the NADH:ubiquinone oxidoreductase determine its dependence on YidC for membrane insertion. J. Biol. Chem. 285:3575-3581. [PM:19959836].
169. Chen, J., Chen, C. L., Rawale, S., Chen, C. A., Zweier, J. L., Kaumaya, P. T., and Chen, Y. R. (2010) Peptide-based antibodies against glutathione-binding domains supress superoxide production mediated by mitochondrial complex I. J. Biol. Chem. 285:3168-3180. [PM:19940158].
170. Galle, A., Florez-Sarasa, I., Thameur, A., De, P. R., Flexas, J., and Ribas-Carbo, M. (2010) Effects of drought stress and subsequent rewatering on photosynthetic and respiratory pathways in Nicotiana sylvestris wild type and the mitochondrial complex I-deficient CMSII mutant. J. Exp. Bot. 61:765-775. [PM:19933320].
171. Baracca, A., Chiaradonna, F., Sgarbi, G., Solaini, G., Alberghina, L., and Lenaz, G. (2010) Mitochondrial Complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells. Biochim. Biophys. Acta 1797:314-323. [PM:19931505].
172. Folbergrova, J., Jesina, P., Haugvicova, R., Lisy, V., and Houstek, J. (2010) Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid. Neurochem. Int. 56:394-403. [PM:19931336].
173. Liu, M., Choi, D. Y., Hunter, R. L., Pandya, J. D., Cass, W. A., Sullivan, P. G., Kim, H. C., Gash, D. M., and Bing, G. (2010) Trichloroethylene Induces Dopaminergic Neurodegeneration in Fisher 344 Rats. J. Neurochem.112:773-783. [PM:19922440].
174. Costa, C., Tozzi, A., Luchetti, E., Siliquini, S., Belcastro, V., Tantucci, M., Picconi, B., Ientile, R., Calabresi, P., and Pisani, F. (2010) Electrophysiological actions of zonisamide on striatal neurons: Selective neuroprotection against complex I mitochondrial dysfunction. Exp. Neurol.221:217-224. [PM:19913015].
175. Dingley, S., Polyak, E., Lightfoot, R., Ostrovsky, J., Rao, M., Greco, T., Ischiropoulos, H., and Falk, M. J. (2010) Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans. Mitochondrion. 10:125-136. [PM:19900588].
176. Davis, C. W., Hawkins, B. J., Ramasamy, S., Irrinki, K. M., Cameron, B. A., Islam, K., Daswani, V. P., Doonan, P. J., Manevich, Y., and Madesh, M. (2010) Nitration of the mitochondrial complex I subunit NDUFB8 elicits. Free Radic. Biol. Med. 48:306-317. [PM:19897030].
177. Zickermann, V., Wumaier, Z., Wrzesniewska, B., Hunte, C., and Schagger, H. (2010) Native immunoblotting of blue native gels (NIBN) to identify conformation-specific antibodies. Proteomics.10:159-163. [PM:19882660].
178. Li, X., Liu, Z., Tamashiro, K., Shi, B., Rudnicki, D. D., Ross, C. A., Moran, T. H., and Smith, W. W. (2010) Synphilin-1 exhibits trophic and protective effects against Rotenone toxicity. Neuroscience165:455-462. [PM:19857556].
179. Brawek, B., Loffler, M., Wagner, K., Huppertz, H. J., Wendling, A. S., Weyerbrock, A., Jackisch, R., and Feuerstein, T. J. (2010) Reactive oxygen species in the human neocortex: role of aging and cognition. Brain Res. Bull.81:484-490. [PM:19854245].
180. Korsten, A., De Coo, I. F., Spruijt, L., de Wit, L. E., Smeets, H. J., and Sluiter, W. (2010) Patients with Leber hereditary optic neuropathy fail to compensate impaired oxidative phosphorylation. Biochim. Biophys. Acta1797:197-203. [PM:19836344].
181. Alakhova, D. Y., Rapoport, N. Y., Batrakova, E. V., Timoshin, A. A., Li, S., Nicholls, D., Alakhov, V. Y., and Kabanov, A. V. (2010) Differential metabolic responses to pluronic in MDR and non-MDR cells: A novel pathway for chemosensitization of drug resistant cancers. J. Control Release 142:89-100. [PM:19815037].
182. Koopman, W. J., Nijtmans, L. G., Dieteren, C. E., Roestenberg, P., Valsecchi, F., Smeitink, J. A., and Willems, P. H. (2010) Mammalian mitochondrial complex I: Biogenesis, Regulation and Reactive Oxygen Species generation. Antioxid. Redox. Signal. [PM:19803744].
183. Jones, T. T. and Brewer, G. J. (2010) Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport. Biochim. Biophys. Acta 1797:167-176. [PM:19799853].
184. Yao, Y. H., Dai, Q., Li, L., Nan, X. Y., He, P. A., and Zhang, Y. Z. (2010) Similarity/dissimilarity studies of protein sequences based on a new 2D graphical representation. J. Comput. Chem. 31:1045-1052. [PM:19777597].
185. Deng, Y. T., Huang, H. C., and Lin, J. K. (2010) Rotenone induces apoptosis in MCF-7 human breast cancer cell-mediated ROS through JNK and p38 signaling. Mol. Carcinog. 49:141-151. [PM:19777565].
186. Dobrynin, K., Abdrakhmanova, A., Richers, S., Hunte, C., Kerscher, S., and Brandt, U. (2010) Characterization of two different acyl carrier proteins in complex I from Yarrowia lipolytica. Biochim. Biophys. Acta 1797:152-159. [PM:19766092].
187. Clason, T., Ruiz, T., Schagger, H., Peng, G., Zickermann, V., Brandt, U., Michel, H., and Radermacher, M. (2010) The structure of eukaryotic and prokaryotic complex I. J. Struct. Biol. 169:81-88. [PM:19732833].
188. Winklhofer, K. F. and Haass, C. (2010) Mitochondrial dysfunction in Parkinson's disease. Biochim. Biophys. Acta 1802:29-44. [PM:19733240].
189. George, A. J., Gordon, L., Beissbarth, T., Koukoulas, I., Holsinger, R. M., Perreau, V., Cappai, R., Tan, S. S., Masters, C. L., Scott, H. S., and Li, Q. X. (2010) A Serial Analysis of Gene Expression Profile of the Alzheimer's Disease Tg2576 Mouse Model. Neurotox. Res. 17:360-379. [PM:19760337].

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