Publications (2001)

  1. Greenamyre, J. T., Sherer, T. B., Betarbet, R., and Panov, A. V. (2001) Complex I and Parkinson's disease. IUBMB. Life 52:135-141.
  2. Iida, A., Saito, S., Sekine, A., Mishima, C., Kondo, K., Kitamura, Y., Harigae, S., Osawa, S., and Nakamura, Y. (2001) Catalog of 258 single-nucleotide polymorphisms (SNPs) in genes encoding three organic anion transporters, three organic anion-transporting polypeptides, and three NADH:ubiquinone oxidoreductase flavoproteins. J. Hum. Genet. 46:668-683.
  3. Schagger, H. (2001) Respiratory chain supercomplexes. IUBMB. Life 52:119-128.
  4. Vicente, J. A., Peixoto, F., Lopes, M. L., and Madeira, V. M. (2001) Differential sensitivities of plant and animal mitochondria to the herbicide paraquat. J. Biochem. Mol. Toxicol. 15:322-330.
  5. Vinogradov, A. D. and Grivennikova, V. G. (2001) The mitochondrial Complex I: progress in understanding of catalytic properties. IUBMB. Life52:129-134.
  6. Yuhki, K. I., Miyauchi, T., Kakinuma, Y., Murakoshi, N., Maeda, S., Goto, K., Yamaguchi, I., and Suzuki, T. (2001) Endothelin-1 production is enhanced by rotenone, a mitochondrial complex I inhibitor, in cultured rat cardiomyocytes. J. Cardiovasc. Pharmacol. 38:850-858.
  7. Vinogradov, A. D. (2001) Respiratory complex I: structure, redox components, and possible mechanisms of energy transduction. Biochemistry (Mosc. ) 66:1086-1097.
  8. Matsushita, K., Otofuji, A., Iwahashi, M., Toyama, H., and Adachi, O. (2001) NADH dehydrogenase of Corynebacterium glutamicum. Purification of an NADH dehydrogenase II homolog able to oxidize NADPH. FEMS Microbiol. Lett. 204:271-276.
  9. Di Bernardo, S. and Yagi, T. (2001) Direct interaction between a membrane domain subunit and a connector subunit in the H+-translocating NADH-quinone oxidoreductase. FEBS Lett. 508:385-388.
  10. Ravn, K., Wibrand, F., Hansen, F. J., Horn, N., Rosenberg, T., and Schwartz, M. (2001) An mtDNA mutation, 14453G-->A, in the NADH dehydrogenase subunit 6 associated with severe MELAS syndrome. Eur. J. Hum. Genet. 9:805-809.
  11. Kim, S. H., Fountoulakis, M., Dierssen, M., and Lubec, G. (2001) Decreased protein levels of complex I 30-kDa subunit in fetal Down syndrome brains. J. Neural Transm. Suppl109-116.
  12. Brown, M. D., Allen, J. C., Van Stavern, G. P., Newman, N. J., and Wallace, D. C. (2001) Clinical, genetic, and biochemical characterization of a Leber hereditary optic neuropathy family containing both the 11778 and 14484 primary mutations. Am. J. Med. Genet. 104:331-338.
  13. Niers, L. E., Smeitink, J. A., Trijbels, J. M., Sengers, R. C., Janssen, A. J., and Van den Heuvel, L. P. (2001) Prenatal diagnosis of NADH:ubiquinone oxidoreductase deficiency. Prenat. Diagn. 21:871-880.
  14. Bar-Meir, M., Elpeleg, O. N., and Saada, A. (2001) Effect of various agents on adenosine triphosphate synthesis in mitochondrial complex I deficiency. J. Pediatr. 139:868-870.
  15. Armstrong, J. S., Hornung, B., Lecane, P., Jones, D. P., and Knox, S. J. (2001) Rotenone-Induced G2/M Cell Cycle Arrest and Apoptosis in a Human B Lymphoma Cell Line PW. Biochem. Biophys. Res. Commun. 289:973-978.
  16. Kerscher, S. J., Eschemann, A., Okun, P. M., and Brandt, U. (2001) External alternative NADH:ubiquinone oxidoreductase redirected to the internal face of the mitochondrial inner membrane rescues complex I deficiency in Yarrowia lipolytica. J. Cell Sci. 114:3915-3921.
  17. Technikova-Dobrova, Z., Sardanelli, A. M., Speranza, F., Scacco, S., Signorile, A., Lorusso, V., and Papa, S. (2001) Cyclic adenosine monophosphate-dependent phosphorylation of Mammalian mitochondrial proteins: enzyme and substrate characterization and functional role. Biochemistry 40:13941-13947.
  18. Tichi, M. A., Meijer, W. G., and Tabita, F. R. (2001) Complex I and Its Involvement in Redox Homeostasis and Carbon and Nitrogen Metabolism in Rhodobacter capsulatus. J. Bacteriol. 183:7285-7294.
  19. Zhang, J. G., Nicholls-Grzemski, F. A., Tirmenstein, M. A., and Fariss, M. W. (2001) Vitamin E succinate protects hepatocytes against the toxic effect of reactive oxygen species generated at mitochondrial complexes I and III by alkylating agents. Chem. Biol. Interact. 138:267-284.
  20. Lomtev, A. S., Sharova, I. V., and Vekshin, N. L. (2001) Flavin and ubiquinone of mitochondrial NADH dehydrogenase are not involved in the electron transfer to artificial acceptors. Dokl. Biochem. Biophys. 376:1-3.
  21. Bertsova, Y. V., Bogachev, A. V., and Skulachev, V. P. (2001) Noncoupled NADH:Ubiquinone Oxidoreductase of Azotobacter vinelandii Is Required for Diazotrophic Growth at High Oxygen Concentrations. J. Bacteriol. 183:6869-6874.
  22. Duby, F., Cardol, P., Matagne, R. F., and Remacle, C. (2001) Structure of the telomeric ends of mt DNA, transcriptional analysis and complex I assembly in the dum24 mitochondrial mutant of Chlamydomonas reinhardtii . Mol. Genet. Genomics 266:109-114.
  23. Triepels, R. H., Van den Heuvel, L. P., Trijbels, J. M., and Smeitink, J. A. (2001) Respiratory chain complex I deficiency. Am. J. Med. Genet. 106:37-45.
  24. Svensson AS, A. S. and Rasmusson, A. G. (2001) Light-dependent gene expression for proteins in the respiratory chain of potato leaves. Plant J. 28:73-82.
  25. Schuler, F. and Casida, J. E. (2001) The insecticide target in the PSST subunit of complex I. Pest. Manag. Sci. 57:932-940.
  26. King, T. D., Bijur, G. N., and Jope, R. S. (2001) Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium. Brain Res. 919:106-114.
  27. Votyakova, T. V. and Reynolds, I. J. (2001) DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria. J. Neurochem. 79:266-277.
  28. Van Coster, R., Smet, J., George, E., De Meirleir, L., Seneca, S., Van Hove, J., Sebire, G., Verhelst, H., De Bleecker, J., Van Vlem, B., Verloo, P., and Leroy, J. (2001) Blue native polyacrylamide gel electrophoresis: a powerful tool in diagnosis of oxidative phosphorylation defects. Pediatr. Res. 50:658-665.
  29. Genova, M. L., Ventura, B., Giuliano, G., Bovina, C., Formiggini, G., Parenti, C. G., and Lenaz, G. (2001) The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron-sulfur cluster N2. FEBS Lett. 505:364-368.
  30. Riobo, N. A., Clementi, E., Melani, M., Boveris, A., Cadenas, E., Moncada, S., and Poderoso, J. J. (2001) Nitric oxide inhibits mitochondrial NADH:ubiquinone reductase activity through peroxynitrite formation. Biochem. J. 359:139-145.
  31. Schagger, H. and Pfeiffer, K. (2001) The ratio of oxidative phosphorylation complexes i-v in bovine heart mitochondria and the composition of respiratory chain supercomplexes. J. Biol. Chem. 276:37861-37867.
  32. Lyddiard, J. R. and Whitfield, P. J. (2001) Inhibition of Site I mitochondrial electron transport by an extract of the seeds of Millettia thonningii: a potential mechanism for the plant's molluscicidal and schistosome larvicidal activity. J. Helminthol. 75:259-265.
  33. Hail, N., Jr. and Lotan, R. (2001) Mitochondrial respiration is uniquely associated with the prooxidant and apoptotic effects of N-(4-hydroxyphenyl)retinamide. J. Biol. Chem. 276:45614-45621
  34. Hase, C. C., Fedorova, N. D., Galperin, M. Y., and Dibrov, P. A. (2001) Sodium ion cycle in bacterial pathogens: evidence from cross-genome comparisons. Microbiol. Mol. Biol. Rev. 65:353-370.
  35. Chauvin, C., De Oliveira, F., Ronot, X., Mousseau, M., Leverve, X. M., and Fontaine, E. (2001) Rotenone inhibits the mitochondrial permeability transition-induced cell death in U937 and KB cells. J. Biol. Chem. 276:41394-41398
  36. Vignais, P. M., Billoud, B., and Meyer, J. (2001) Classification and phylogeny of hydrogenases(1). FEMS Microbiol. Rev. 25:455-501.
  37. Fearnley, I. M., Carroll, J., Shannon, R. J., Runswick, M. J., Walker, J. E., and Hirst, J. (2001) GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH: Ubiquinone oxidoreductase (complex I). J. Biol. Chem. 276:38345-38348
  38. Cleeter, M. W., Cooper, J. M., and Schapira, A. H. (2001) Nitric oxide enhances MPP+ inhibition of complex I. FEBS Lett. 504:50-52.
  39. Rich, P. R., Mischis, L. A., Purton, S., and Wiskich, J. T. (2001) The sites of interaction of triphenyltetrazolium chloride with mitochondrial respiratory chains. FEMS Microbiol. Lett. 202:181-187.
  40. Zhang, J. G., Tirmenstein, M. A., Nicholls-Grzemski, F. A., and Fariss, M. W. (2001) Mitochondrial electron transport inhibitors cause lipid peroxidation-dependent and -independent cell death: protective role of antioxidants. Arch. Biochem. Biophys. 393:87-96.
  41. Kingsbury, A. E., Cooper, M., Schapira, A. H., and Foster, O. J. (2001) Metabolic enzyme expression in dopaminergic neurons in Parkinson's disease: an in situ hybridization study. Ann. Neurol. 50:142-149.
  42. Di Giovanni, S., Mirabella, M., Spinazzola, A., Crociani, P., Silvestri, G., Broccolini, A., Tonali, P., Di Mauro, S., and Servidei, S. (2001) Coenzyme Q10 reverses pathological phenotype and reduces apoptosis in familial CoQ(10) deficiency. Neurology 57:515-518.
  43. Grandier-Vazeille, X., Bathany, K., Chaignepain, S., Camougrand, N., Manon, S., and Schmitter, J. M. (2001) Yeast mitochondrial dehydrogenases are associated in a supramolecular complex. Biochemistry 40:9758-9769.
  44. Remacle, C., Duby, F., Cardol, P., and Matagne, R. F. (2001) Mutations inactivating mitochondrial genes in Chlamydomonas reinhardtii. Biochem. Soc. Trans. 29:442-446.
  45. Brown, M. D., Zhadanov, S., Allen, J. C., Hosseini, S., Newman, N. J., Atamonov, V. V., Mikhailovskaya, I. E., Sukernik, R. I., and Wallace, D. C. (2001) Novel mtDNA mutations and oxidative phosphorylation dysfunction in Russian LHON families. Hum. Genet. 109:33-39.
  46. Bai, Y., Hajek, P., Chomyn, A., Chan, E., Seo, B. B., Matsuno-Yagi, A., Yagi, T., and Attardi, G. (2001) Lack of complex I activity in human cells carrying a mutation in mtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene. J. Biol. Chem. 276:38808-38813
  47. Hamilton, E. W., III and Heckathorn, S. A. (2001) Mitochondrial adaptations to NaCl. Complex I is protected by anti-oxidants and small heat shock proteins, whereas complex II is protected by proline and betaine. Plant Physiol 126:1266-1274.
  48. Taivassalo, T., Shoubridge, E. A., Chen, J., Kennaway, N. G., DiMauro, S., Arnold, D. L., and Haller, R. G. (2001) Aerobic conditioning in patients with mitochondrial myopathies: physiological, biochemical, and genetic effects. Ann. Neurol. 50:133-141.
  49. Matsuno-Yagi, A. and Yagi, T. (2001) Introduction: Complex I - an L-shaped black box. J. Bioenerg. Biomembr. 33:155-157.
  50. Dupuis, A., Prieur, I., and Lunardi, J. (2001) Toward a characterisation of the connecting module of Complex I. J. Bioenerg. Biomembr. 33:159-168.
  51. Friedrich, T. (2001) Complex I: A chimera of a redox and conformation driven proton pump?. J. Bioenerg. Biomembr. 33:169-177.
  52. Julia Steuber, J. (2001) The Na+-translocating NADH: quinone oxidoreductase (NDHI) from Klebsiella pneumoniae and Escherichia coli: implications for the mechanism of redox-driven cation translocation by complex I. J. Bioenerg. Biomembr. 33:179-186.
  53. Kerscher, S., Kashani-Poor, N., Zwicker, K., Zickermann, V. and Brandt, U. (2001) Exploring the catalytic core of Complex I by Yarrowia lipolytica yeast genetics. J. Bioenerg. Biomembr. 33:187-196.
  54. Videira, A. and Duarte, M. (2001) On Complex I and other NADH:ubiquinone reductases of Neurospora crassa mitochondria. J. Bioenerg. Biomembr. 33:197-203.
  55. Schulte, U. (2001) Biogenesis of respiratory complex I. J. Bioenerg. Biomembr. 33:205-212.
  56. Yano, T. and Ohnishi, T. (2001) The origin of cluster N2 of the energy-transducing NADH-quinone oxidoreductase: Comparisons of phylogenetically related enzymes. J. Bioenerg. Biomembr. 33:213-222.
  57. Miyoshi, H. (2001) Probing the ubiquinone reduction site in bovine mitochondrial complex I using a series of synthetic ubiquinones and inhibitors. J. Bioenerg. Biomembr. 33:223-231.
  58. Yagi, T., Seo, B. B., Di Bernardo, S., Nakamaru-Ogiso, E., Kao, M.-C. and Matsuno-Yagi, A. (2001) Research on NADH dehydrogenases: From basic science to biomedicine. J. Bioenerg. Biomembr. 33:233-242.
  59. Scheffler, I. E. and Yadava, N. (2001) Molecular Genetics of the mammalian NADH-ubiquinone oxidoreductase. J. Bioenerg. Biomembr. 33:243-250.
  60. Chomyn, A. (2001) The identification of the mitochondrial DNA-encoded subunits of mammalian complex I and their role in the complex J. Bioenerg. Biomembr. 33:251-257.
  61. Smeitink, J., Sengers, R., Trijbels, F. and van den Heuvel, L. (2001) Human NADH:ubiquinone oxidoreductase. J. Bioenerg. Biomembr. 33:259-266.
  62. Taylor, R. W., Singh-Kler, R., Hayes, C. M., Smith, P. E., and Turnbull, D. M. (2001) Progressive mitochondrial disease resulting from a novel missense mutation in the mitochondrial DNA ND3 gene. Ann. Neurol. 50:104-107.
  63. Remacle, C., Baurain, D., Cardol, P., and Matagne, R. F. (2001) Mutants of Chlamydomonas reinhardtii Deficient in Mitochondrial Complex I. Characterization of two mutations affecting the nd1 coding sequence. Genetics 158:1051-1060.
  64. Kedra, A. H., Tkach, V. V., Swiderski, Z., Pawl&z shtsls, and owski, Z. (2001) Intraspecific variability among NADH dehydrogenase subunit 1 sequences of Taenia hydatigena. Parasitol. Int. 50:145-148.
  65. Gredilla, R., Sanz, A., Lopez-Torres, M., and Barja, G. (2001) Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart. FASEB J. 15:1589-1591.
  66. Fonck, C. and Baudry, M. (2001) Toxic effects of MPP + and MPTP in PC12 cells independent of reactive oxygen species formation. Brain Res. 905:199-206.
  67. Schuler, F. and Casida, J. E. (2001) Functional coupling of PSST and ND1 subunits in NADH:ubiquinone oxidoreductase established by photoaffinity labeling. Biochim. Biophys. Acta 1506:79-87.
  68. Tsang, W. Y., Sayles, L. C., Grad, L. I., Pilgrim, D. B., and Lemire, B. D. (2001) Mitochondrial respiratory chain deficiency in Caenorhabditis elegans results in developmental arrest and increased lifespan. J. Biol. Chem.
  69. Conn, K. J., Ullman, M. D., Eisenhauer, P. B., Fine, R. E., and Wells, J. M. (2001) Decreased expression of the NADH:ubiquinone oxidoreductase (complex I) subunit 4 in 1-methyl-4-phenylpyridinium -treated human neuroblastoma SH-SY5Y cells. Neurosci. Lett. 306:145-148.
  70. Bogachev, A. V., Bertsova, Y. V., Barquera, B., and Verkhovsky, M. I. (2001) Sodium-dependent steps in the redox reactions of the Na+-motive NADH:quinone oxidoreductase from Vibrio harveyi. Biochemistry 40:7318-7323.
  71. Kim, S. H., Vlkolinsky, R., Cairns, N., Fountoulakis, M., and Lubec, G. (2001) The reduction of NADH ubiquinone oxidoreductase 24- and 75-kDa subunits in brains of patients with Down syndrome and Alzheimer's disease. Life Sci. 68:2741-2750.
  72. van den, H. L. and Smeitink, J. (2001) The oxidative phosphorylation (OXPHOS) system: nuclear genes and human genetic diseases. Bioessays 23:518-525.
  73. Scheffler, I. E. (2001) Mitochondria make a come back. Adv. Drug Deliv. Rev. 49:3-26.
  74. Velazquez, I. and Pardo, J. P. (2001) Kinetic characterization of the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae. Arch. Biochem. Biophys. 389:7-14.
  75. Swerdlow, R. H., Parks, J. K., Cassarino, D. S., Binder, D. R., Bennett, J. P., Jr., Di Iorio, G., Golbe, L. I., and Parker, W. D., Jr. (2001) Biochemical analysis of cybrids expressing mitochondrial DNA from Contursi kindred Parkinson's subjects. Exp. Neurol. 169:479-485.
  76. Benit, P., Chretien, D., Kadhom, N., Lonlay-Debeney, P., Cormier-Daire, V., Cabral, A., Peudenier, S., Rustin, P., Munnich, A., and Rotig, A. (2001) Large-scale deletion and point mutations of the nuclear NDUFV1 and NDUFS1 genes in mitochondrial complex I deficiency. Am. J. Hum. Genet. 68:1344-1352.
  77. Fang, J., Wang, Y., and Beattie, D. S. (2001) Isolation and characterization of complex I, rotenone-sensitive NADH:ubiquinone oxidoreductase, from the procyclic forms of Trypanosoma brucei. Eur. J. Biochem. 268:3075-3082.
  78. Schnorpfeil, M., Janausch, I. G., Biel, S., Kroger, A., and Unden, G. (2001) Generation of a proton potential by succinate dehydrogenase of Bacillus subtilis functioning as a fumarate reductase. Eur. J. Biochem. 268:3069-3074.
  79. Kashino, Y., Koike, H., and Satoh, K. (2001) An improved sodium dodecyl sulfate-polyacrylamide gel electrophoresis system for the analysis of membrane protein complexes. Electrophoresis 22:1004-1007.
  80. Rasmussen, T., Scheide, D., Brors, B., Kintscher, L., Weiss, H., and Friedrich, T. (2001) Identification of two tetranuclear fes clusters on the ferredoxin-type subunit of nadh:ubiquinone oxidoreductase (complex i). Biochemistry 40:6124-6131.
  81. Ebadi, M., Govitrapong, P., Sharma, S., Muralikrishnan, D., Shavali, S., Pellett, L., Schafer, R., Albano, C., and Eken, J. (2001) Ubiquinone (coenzyme q(10)) and mitochondria in oxidative stress of parkinson's disease. Biol. Signals Recept. 10:224-253.
  82. Zhang, Q., Soole, K. L., and Wiskich, J. T. (2001) Regulation of respiration in rotenone-treated tobacco cell suspension cultures. Planta 212:765-773.
  83. Kashani-Poor, N., Zwicker, K., Kerscher, S., and Brandt, U. (2001) A central functional role for the 49 kDa subunit within the catalytic core of mitochondrial complex I. J. Biol. Chem. 276:24082-24087.
  84. Hamilton, A. (2001) Phylogeny of limia (teleostei: poeciliidae) based on nadh dehydrogenase subunit 2 sequences. Mol. Phylogenet. Evol. 19:277-289.
  85. Banaclocha, M. M. (2001) Therapeutic potential of N-acetylcysteine in age-related mitochondrial neurodegenerative diseases. Med. Hypotheses 56:472-477.
  86. Sammut, I. A., Jayakumar, J., Latif, N., Rothery, S., Severs, N. J., Smolenski, R. T., Bates, T. E., and Yacoub, M. H. (2001) Heat stress contributes to the enhancement of cardiac mitochondrial complex activity. Am. J. Pathol. 158:1821-1831.
  87. Moreira, M. E., Sorensen, A. C., Heard, K. J., Harken, A. H., Banerjee, A., and Cairns, C. B. (2001) Reduction in the mitochondrial energy potential by inhibition of electron transport in human vascular smooth muscle cells. Acad. Emerg. Med. 8:548-
  88. Heard, K. J., Moreira, M. E., Sorensen, A. C., Harken, A. H., Banerjee, A., and Cairns, C. B. (2001) Rapid restoration of the mitochondrial energy potential after azt in human cells. Acad. Emerg. Med. 8:442-
  89. Briet, F. and Jeejeebhoy, K. N. (2001) Effect of hypoenergetic feeding and refeeding on muscle and mononuclear cell activities of mitochondrial complexes I-IV in enterally fed rats. Am. J. Clin. Nutr. 73:975-983.
  90. Pahlman, I. L., Gustafsson, L., Rigoulet, M., and Larsson, C. (2001) Cytosolic redox metabolism in aerobic chemostat cultures of Saccharomyces cerevisiae. Yeast 18:611-620.
  91. Hino, A., Morita, M., Une, M., Fujimura, K., and Kuramoto, T. (2001) Effects of deoxycholic acid and its epimers on lipid peroxidation in isolated rat hepatocytes. J. Biochem. (Tokyo) 129:683-689.
  92. Cormier, A., Morin, C., Zini, R., Tillement, J., and Lagrue, G. (2001) In vitro effects of nicotine on mitochondrial respiration and superoxide anion generation. Brain Res. 900:72-79.
  93. Lin, E., Graziano, J. H., and Freyer, G. A. (2001) The Regulation of the 75 kDa subunit of Mitochondrial Complex I by Iron. J. Biol. Chem. 276: 27685-27692.
  94. Jenner, P. (2001) Parkinson's disease, pesticides and mitochondrial dysfunction. Trends Neurosci. 24:245-246.
  95. Pearce, L. L., Epperly, M. W., Greenberger, J. S., Pitt, B. R., and Peterson, J. (2001) Identification of respiratory complexes i and iii as mitochondrial sites of damage following exposure to ionizing radiation and nitric oxide. Nitric. Oxide. 5:128-136.
  96. Hase, C. C. and Barquera, B. (2001) Role of sodium bioenergetics in Vibrio cholerae. Biochim. Biophys. Acta 1505:169-178.
  97. Balijepalli, S., Kenchappa, R. S., Boyd, M. R., and Ravindranath, V., V (2001) Protein thiol oxidation by haloperidol results in inhibition of mitochondrial complex I in brain regions: comparison with atypical antipsychotics. Neurochem. Int. 38:425-435.
  98. Klivenyi, P., Karg, E., Rozsa, C., Horvath, R., Komoly, S., Nemeth, I., Turi, S., and Vecsei, L. (2001) alpha-Tocopherol/lipid ratio in blood is decreased in patients with Leber's hereditary optic neuropathy and asymptomatic carriers of the 11778 mtDNA mutation. J. Neurol. Neurosurg. Psychiatry 70:359-362.
  99. Triepels, R. H., Hanson, B. J., Van den Heuvel, L. P., Sundell, L., Marusich, M. F., Smeitink, J. A., and Capaldi, R. A. (2001) Human Complex I Defects Can Be Resolved by Monoclonal Antibody Analysis into Distinct Subunit Assembly Patterns. J. Biol. Chem. 276:8892-8897.
  100. Tormo, J. R., Estornell, E., Gallardo, T., Gonzalez, M. C., Cave, A., Granell, S., Cortes, D., and Zafra-Polo, M. C. (2001) Gamma-lactone-Functionalized antitumoral acetogenins are the most potent inhibitors of mitochondrial complex I. Bioorg. Med. Chem. Lett. 11:681-684.
  101. Barquera, B., Hase, C. C., and Gennis, R. B. (2001) Expression and mutagenesis of the NqrC subunit of the NQR respiratory Na+ pump from Vibrio cholerae with covalently attached FMN. FEBS Lett. 492:45-49.
  102. Kashani-Poor, N., Kerscher, S., Zickermann, V., and Brandt, U. (2001) Efficient large scale purification of his-tagged proton translocating NADH:ubiquinone oxidoreductase (complex I) from the strictly aerobic yeast Yarrowia lipolytica. Biochim. Biophys. Acta 1504:363-370.
  103. Roth, R. and Hagerhall, C. (2001) Transmembrane orientation and topology of the NADH:quinone oxidoreductase putative quinone binding subunit NuoH. Biochim. Biophys. Acta 1504:352-362.
  104. Joseph-Horne, T., Hollomon, D. W., and Wood, P. M. (2001) Fungal respiration: a fusion of standard and alternative components. Biochim. Biophys. Acta 1504:179-195.
  105. Prieur, I., Lunardi, J., and Dupuis, A. (2001) Evidence for a quinone binding site close to the interface between NUOD and NUOB subunits of Complex I. Biochim. Biophys. Acta 1504:173-178.
  106. Casano, L. M., Martin, M., and Sabater, B. (2001) Hydrogen peroxide mediates the induction of chloroplastic ndh complex under photooxidative stress in barley. Plant Physiol 125:1450-1458.
  107. Miyadera, H., Amino, H., Hiraishi, A., Taka, H., Murayama, K., Miyoshi, H., Sakamoto, K., Ishii, N., Hekimi, S., and Kita, K. (2001) Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans. J. Biol. Chem. 276:7713-7716.
  108. De Kremer, R. D., Paschini-Capra, A., Bacman, S., Argarana, C., Civallero, G., Kelley, R. I., Guelbert, N., Latini, A., de Halac, I. N., Giner-Ayala, A., Johnston, J., Proujansky, R., Gonzalez, I., Depetris-Boldini, C., Oller-Ramirez, A., Angaroni, C., Theaux, R. A., Hliba, E., and Juaneda, E. (2001) Barth's syndrome-like disorder: A new phenotype with a maternally inherited A3243G substitution of mitochondrial DNA (MELAS mutation). Am. J. Med. Genet. 99:83-93.
  109. Vasquez, O. L., Almeida, A. A., and Bolanos, J. P. (2001) Depletion of glutathione up-regulates mitochondrial complex I expression in glial cells. J. Neurochem. 76:1593-1596.
  110. Loeffen, J., Elpeleg, O., Smeitink, J., Smeets, R., Stockler-Ipsiroglu, S., Mandel, H., Sengers, R., Trijbels, F., and van den, H. L. (2001) Mutations in the complex I NDUFS2 gene of patients with cardiomyopathy and encephalomyopathy. Ann. Neurol. 49:195-201.
  111. Corona, P., Antozzi, C., Carrara, F., D'Incerti, L., Lamantea, E., Tiranti, V., and Zeviani, M. (2001) A novel mtDNA mutation in the ND5 subunit of complex I in two MELAS patients. Ann. Neurol. 49:106-110.
  112. Papa, S., Scacco, S., Sardanelli, A. M., Vergari, R., Papa, F., Budde, S., van den, H. L., and Smeitink, J. (2001) Mutation in the NDUFS4 gene of complex I abolishes cAMP-dependent activation of the complex in a child with fatal neurological syndrome. FEBS Lett. 489:259-262.
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