Publications (2000)

  1. Janssens, D., Delaive, E., Remacle, J., and Michiels, C. (2000) Protection by bilobalide of the ischaemia-induced alterations of the mitochondrial respiratory activity. Fundam. Clin. Pharmacol. 14:193-201. [PM:15602795].
  2. Arroyo, A., Navarro, F., Gomez-Diaz, C., Crane, F. L., Alcain, F. J., Navas, P., and Villalba, J. M. (2000) Interactions between ascorbyl free radical and coenzyme Q at the plasma membrane. J. Bioenerg. Biomembr. 32:199-210.
  3. McLennan, H. R. and Degli, E. M. (2000) The contribution of mitochondrial respiratory complexes to the production of reactive oxygen species. J. Bioenerg. Biomembr. 32:153-162.
  4. Elias, D. A., Juck, D. F., Berry, K. A., and Sparling, R. (2000) Purification of the NADP+:F420 oxidoreductase of Methanosphaera stadtmanae . Can. J. Microbiol. 46:998-1003.
  5. Takada, M., Kuwabara, K., Nakato, H., Tanaka, A., Iwamura, H., and Miyoshi, H. (2000) Definition of crucial structural factors of acetogenins, potent inhibitors of mitochondrial complex I. Biochim. Biophys. Acta 1460:302-310.
  6. Batandier, C., Picard, A., Tessier, N., and Lunardi, J. (2000) Identification of a novel T398A mutation in the ND5 subunit of the mitochondrial complex I and of three novel mtDNA polymorphisms in two patients presenting ocular symptoms . Hum. Mutat. 16:532-
  7. Thiffault, C., Langston, J. W., and Di Monte, D. A. (2000) Increased striatal dopamine turnover following acute administration of rotenone to mice. Brain Res. 885:283-288.
  8. Betarbet, R., Sherer, T. B., MacKenzie, G., Garcia-Osuna, M., Panov, A. V., and Greenamyre, J. T. (2000) Chronic systemic pesticide exposure reproduces features of Parkinson's disease . Nat. Neurosci. 3:1301-1306.
  9. Ohkubo, E., Aida, K., Chen, J., Hayashi, J. I., Isobe, K., Tawata, M., and Onaya, T. (2000) A patient with type 2 diabetes mellitus associated with mutations in calcium sensing receptor gene and mitochondrial DNA . Biochem. Biophys. Res. Commun. 278:808-813.
  10. Albracht, S. P. and Hedderich, R. (2000) Learning from hydrogenases: location of a proton pump and of a second FMN in bovine NADH-ubiquinone oxidoreductase (Complex I) . FEBS Lett. 485:1-6.
  11. Koitabashi, T., Satoh, T., and Koyama, N. (2000) Peroxide Reductase Activity of NADH Dehydrogenase in the Presence of an Endogenous 20-kDa Component of an Alkaliphilic Bacillus. Curr. Microbiol. 41:388-391.
  12. Sabar, M., De Paepe, R., and De Kouchkovsky, Y. (2000) Complex I impairment, respiratory compensations, and photosynthetic decrease in nuclear and mitochondrial male sterile mutants of nicotiana sylvestris . Plant Physiol 124:1239-1250.
  13. Talpade, D. J., Greene, J. G., Higgins, D. S., Jr., and Greenamyre, J. T. (2000) In vivo labeling of mitochondrial complex I (NADH:Ubiquinone oxidoreductase) in rat brain using [3H]Dihydrorotenone . J. Neurochem. 75:2611-2621.
  14. Kunz, W. S., Kudin, A. P., Vielhaber, S., Blumcke, I., Zuschratter, W., Schramm, J., Beck, H., and Elger, C. E. (2000) Mitochondrial complex I deficiency in the epileptic focus of patients with temporal lobe epilepsy . Ann. Neurol. 48:766-773.
  15. Ohkawa, H., Pakrasi, H. B., and Ogawa T. (2000) Two types of functionally distinct NAD(P)H dehydrogenases in synechocystis sp. Strain PCC6803. J. Biol. Chem. 275:31630-31634.
  16. Kurki, S., Zickermann, V., Kervinen, M., Hassinen, I., and Finel, M. (2000) Mutagenesis of three conserved Glu residues in a bacterial homologue of the ND1 subunit of complex I affects ubiquinone reduction kinetics but not inhibition by dicyclohexylcarbodiimide. Biochemistry 39:13496-13502.
  17. Smith, M. A., Finel, M., Korolik, V., and Mendz, G. L. (2000) Characteristics of the aerobic respiratory chains of the microaerophiles Campylobacter jejuni and Helicobacter pylori. Arch. Microbiol. 174:1-10.
  18. Duarte, M. and Videira, A. (2000) Respiratory chain complex I is essential for sexual development in Neurospora and binding of iron sulfur clusters are required for enzyme assembly. Genetics 156:607-615.
  19. Bautista, J., Corpas, R., Ramos, R., Cremades, O., Gutierrez, J. F., and Alegre, S. (2000) Brain mitochondrial complex I inactivation by oxidative modification . Biochem. Biophys. Res. Commun. 275:890-894.
  20. Lotharius, J. and O'Malley, K. L. (2000) The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium (MPP+) triggers intracellular dopamine oxidation: a novel mechanism of toxicity. J. Biol. Chem. 275:38581-38588.
  21. Procaccio, V., Lescuyer, P., Bourges, I., Beugnot, R., Duborjal, H., Depetris, D., Mousson, B., Montfort, M. F., Smeets, H., De Coo, R., and Issartel, J. P. (2000) Human NDUFS3 gene coding for the 30-kDa subunit of mitochondrial complex I: genomic organization and expression. Mamm. Genome 11:808-810.
  22. Agani, F. H., Pichiule, P., Chavez, J. C., and LaManna, J. C. (2000) The role of mitochondria in the regulation of hypoxia-inducible factor-1 expression during hypoxia. J. Biol. Chem. 275:35863-35867.
  23. Jha, N., Jurma, O., Lalli, G., Liu, Y., Pettus, E. H., Greenamyre, J. T., Liu, R. M., Forman, H. J., Andersen, J. K., Borutaite, V., Budriunaite, A., and Brown, G. C. (2000) Glutathione depletion in PC12 results in selective inhibition of mitochondrial complex I activity. Implications for Parkinson's disease
    Reversal of nitric oxide-, peroxynitrite- and S-nitrosothiol-induced inhibition of mitochondrial respiration or complex I activity by light and thiols
    . J. Biol. Chem. 275:26096-26101.
  24. Friedrich, T., Brors, B., Hellwig, P., Kintscher, L., Rasmussen, T., Scheide, D., Schulte, U., Mantele, W., and Weiss, H. (2000) Characterization of two novel redox groups in the respiratory NADH:ubiquinone oxidoreductase (complex I). Biochim. Biophys. Acta 1459:305-309.
  25. Yano, T., Magnitsky, S., and Ohnishi, T. (2000) Characterization of the complex I-associated ubisemiquinone species: toward the understanding of their functional roles in the electron/proton transfer reaction. Biochim. Biophys. Acta 1459:299-304.
  26. Kerscher, S. J. (2000) Diversity and origin of alternative NADH:ubiquinone oxidoreductases. Biochim. Biophys. Acta 1459:274-283.
  27. Ahlers, P. M., Garofano, A., Kerscher, S. J., and Brandt, U. (2000) Application of the obligate aerobic yeast Yarrowia lipolytica as a eucaryotic model to analyse Leigh syndrome mutations in the complex I core subunits PSST and TYKY. Biochim. Biophys. Acta 1459:258-265.
  28. McNaught, K. S. and Jenner, P. (2000) Extracellular accumulation of nitric oxide, hydrogen peroxide, and glutamate in astrocytic cultures following glutathione depletion, complex I inhibition, and/or lipopolysaccharide-induced activation . Biochem. Pharmacol. 60:979-988.
  29. Annepu, J. and Ravindranath, V. (2000) 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced complex I inhibition is reversed by disulfide reductant, dithiothreitol in mouse brain . Neurosci. Lett. 289:209-212.
  30. Budde, S. M., Van den Heuvel, L. P., Janssen, A. J., Smeets, R. J., Buskens, C. A., DeMeirleir, L., Van Coster, R., Baethmann, M., Voit, T., Trijbels, J. M., and Smeitink, J. A. (2000) Combined enzymatic complex I and III deficiency associated with mutations in the nuclear encoded NDUFS4 gene. Biochem. Biophys. Res. Commun. 275:63-68.
  31. Friedrich, T. and Scheide, D. (2000) The respiratory complex I of bacteria, archaea and eukarya and its module common with membrane-bound multisubunit hydrogenases. FEBS Lett. 479:1-5.
  32. Tormo, J. R., Zafra-Polo, M. C., Serrano, A., Estornell, E., and Cortes, D. (2000) Epoxy-acetogenins and other polyketide epoxy derivatives as inhibitors of the mitochondrial respiratory chain complex I. Planta Med. 66:318-323.
  33. Seo, B. B., Wang, J., Flotte, T. R., Yagi, T., and Matsuno-Yagi, A. (2000) Use of the NADH-Quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae as a possible cure for complex I defects in human cells. J. Biol. Chem. 275:37774-37778.
  34. Scharfe, C., Hauschild, M., Klopstock, T., Janssen, A. J., Heidemann, P. H., Meitinger, T., and Jaksch, M. (2000) A novel mutation in the thiamine responsive megaloblastic anaemia gene SLC19A2 in a patient with deficiency of respiratory chain complex I . J. Med. Genet. 37:674-679.
  35. Hellwig, P., Scheide, D., Bungert, S., Mantele, W., and Friedrich, T. (2000) FT-IR spectroscopic characterization of NADH:Ubiquinone oxidoreductase (Complex I) from escherichia coli: oxidation of FeS cluster N2 is coupled with the protonation of an aspartate or glutamate side chain . Biochemistry 39:10884-10891.
  36. Brown, M. D., Trounce, I. A., Jun, A. S., Allen, J. C., and Wallace, D. C. (2000) Functional analysis of lymphoblast and cybrid mitochondria containing the 3460, 11778, or 14484 Leber's Hereditary Optic Neuropathy mtDNA mutations. J. Biol. Chem. 275: 39831-39836.
  37. Bautista, J., Corpas, R., Ramos, R., Cremades, O., Gutierrez, J. F., and Alegre, S. (2000) Brain Mitochondrial Complex I Inactivation by Oxidative Modification. Biochem. Biophys. Res. Commun. 275:890-894.
  38. Bruggemann, H., Falinski, F., and Deppenmeier, U. (2000) Structure of the F420H2:quinone oxidoreductase of Archaeoglobus fulgidus Identification and overproduction of the F420H2-oxidizing subunit. Eur. J. Biochem. 267:5810-5814.
  39. Sazanov, L. A. and Walker, J. E. (2000) Cryo-electron Crystallography of Two Sub-complexes of Bovine Complex I Reveals the Relationship between the Membrane and Peripheral Arms. J. Mol. Biol. 302:455-464.
  40. Procaccio, V., Lescuyer, P., Bourges, I., Beugnot, R., Duborjal, H., Depetris, D., Mousson, B., Montfort, M. F., Smeets, H., De Coo, R., and Issartel, J. P. (2000) Human NDUFS3 gene coding for the 30-kDa subunit of mitochondrial complex I: genomic organization and expression. Mamm. Genome 11:808-810.
  41. Xin, W., Shen, X. M., Li, H., and Dryhurst, G. (2000) Oxidative Metabolites of 5-S-Cysteinylnorepinephrine Are Irreversible Inhibitors of Mitochondrial Complex I and the alpha-Ketoglutarate Dehydrogenase and Pyruvate Dehydrogenase Complexes: Possible Implications for Neurodegenerative Brain Disorders. Chem. Res. Toxicol. 13:749-760.
  42. Jha, N., Jurma, O., Lalli, G., Liu, Y., Pettus, E. H., Greenamyre, J. T., Liu, R. M., Forman, H. J., and Andersen, J. K. (2000) Glutathione depletion in PC12 results in selective inhibition of mitochondrial complex I activity. IMPLICATIONS FOR PARKINSON'S DISEASE. J. Biol. Chem. 275:26096-26101.
  43. Di Bernardo, S., Yano, T., and Yagi, T. (2000) Exploring the Membrane Domain of the Reduced Nicotinamide Adenine Dinucleotide-Quinone Oxidoreductase of Paracoccus denitrificans: Characterization of the NQO7 Subunit. Biochemistry 39:9411-9418.
  44. Owen, M. R., Doran, E., and Halestrap, A. P. (2000) Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem. J. 348 Pt 3:607-614.
  45. Pettus, E. H., Betarbet, R., Cottrell, B., Wallace, D. C., Madyastha, V., and Greenamyre, J. T. (2000) Immunocytochemical characterization of the mitochondrially encoded ND1 subunit of complex I (NADH : ubiquinone oxidoreductase) in rat brain. J. Neurochem. 75:383-392.
  46. Parrado, J., Absi, E., Ayala, A., Castano, A., Cano, J., and Machado, A. (2000) The endogenous amine 1-methyl-1,2,3,4-tetrahydroisoquinoline prevents the inhibition of complex I of the respiratory chain produced by MPP+. J. Neurochem. 75:65-71.
  47. Elbehti, A., Brasseur, G., and Lemesle-Meunier, D. (2000) First evidence for existence of an uphill electron transfer through the bc(1) and NADH-Q oxidoreductase complexes of the acidophilic obligate chemolithotrophic ferrous ion-oxidizing bacterium Thiobacillus ferrooxidans. J. Bacteriol. 182:3602-3606.
  48. Djafarzadeh, R., Kerscher, S., Zwicker, K., Radermacher, M., Lindahl, M., Schagger, H., and Brandt, U. (2000) Biophysical and structural characterization of proton-translocating NADH-dehydrogenase (complex I) from the strictly aerobic yeast Yarrowia lipolytica. Biochim. Biophys. Acta 1459:230-238.
  49. Okun, J. G., Zickermann, V., Zwicker, K., Schagger, H., a nd Brandt, U. (2000) Binding of detergents and inhibitors to bovine complex I - a novel purification procedure for bovine complex I retaining full inhibitor sensitivity. Biochim. Biophys. Acta 1459:77-87.
  50. Zickermann V, Kurki, S., Kervinen, M., Hassinen, I., and Finel, M. (2000) The NADH oxidation domain of Complex I: do bacterial and mitochondrial enzymes catalyze ferricyanide reduction similarly? Biochim. Biophys. Acta 1459:61-68.
  51. Nakamura, K., Bindokas, V. P., Marks, J. D., Wright, D. A., Frim, D. M., Miller, R. J., and Kang, U. J. (2000) The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: the role of mitochondrial complex I and reactive oxygen species revisited. Mol. Pharmacol. 58:271-278.
  52. Ahlers, P. M., Zwicker, K., Kerscher, S., and Brandt, U. (2000) Function of Conserved Acidic Residues in the PSST-Homologue of Complex I (NADH: Ubiquinone Oxidoreductase) from Yarrowia lipolytica. J. Biol. Chem. 275:23577-23582.
  53. Nakayama, Y., Yasui, M., Sugahara, K., Hayashi, M, and Unemoto, T. (2000) Covalently bound flavin in the NqrB and NqrC subunits of Na+-translocating NADH-quinone reductase from Vibrio alginolyticus. FEBS Lett. 474:165-168.
  54. Sazanov, L.A., Peak-Chew, S.W., Fearnley, I.M., and Walker, J.E. (2000) Resolution of the Membrane Domain of Bovine Complex I into Subcomplexes: Implications for the Structural Organization of the Enzyme. Biochemistry 39:7229-7235.
  55. Barker, H. C., Kinsella, N., Jaspe, A., Friedrich, T., and O'Connor, C. D. (2000) Formate protects stationary-phase Escherichia coli and Salmomella cells from killing by a cationic antimicrobial peptide. Molec. Microbiol. 35:1518-1529.
  56. del Campo, E. M., Sabater, B., and Martin, M. (2000) Transcripts of the ndhH-D operon of barley plastids: possible role of unedited site III in splicing of the ndhA intron. Nucleic Acids Res. 28:1092-1098.
  57. Seyfried, J., Soldner, F., Kunz, W. S., Schulz, J. B., Klockgether, T., Kovar, K. A., and Wullner, U. (2000) Effect of 1-methyl-4-phenylpyridinium on glutathione in rat pheochromocytoma PC 12 cells. Neurochem. Int. 36:489-497.
  58. Cassarino, D. S., Halvorsen, E. M., Swerdlow, R. H., Abramova, N. N., Parker, W. D., Jr., Sturgill, T. W., and Bennett, J. P., Jr. (2000) Interaction among mitochondria, mitogen-activated protein kinases, and nuclear factor-kappaB in cellular models of Parkinson's disease. J. Neurochem. 74:1384-1392.
  59. Martinez, B. M. (2000) N-acetylcysteine elicited increase in complex I activity in synaptic mitochondria from aged mice: implications for treatment of Parkinson's disease. Brain Res. 859:173-175.
  60. Weinberg, J. M., Venkatachalam, M. A., Roeser, N. F., and Nissim, I. (2000) Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates. Proc. Natl. Acad. Sci. U.S.A. 97:2826-2831.
  61. Kashiwaya, Y., Takeshima, T., Mori, N., Nakashima, K., Clarke, K., and Veech, R. L. (2000) D-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease . Proc. Natl. Acad. Sci. U.S.A. 97:5440-5444.
  62. Lamensdorf, I., Eisenhofer, G., Harvey-White, J., Hayakawa, Y., Kirk, K., and Kopin, I. J. (2000) Metabolic stress in PC12 cells induces the formation of the endogenous dopaminergic neurotoxin, 3,4-dihydroxyphenylacetaldehyde. J. Neurosci. Res. 60:552-558.
  63. Kuwabara, K., Takada, M., Iwata, J., Tatsumoto, K., Sakamoto, K., Iwamura, H., and Miyoshi, H. (2000) Design syntheses and mitochondrial complex I inhibitory activity of novel acetogenin mimics. Eur. J. Biochem. 267:2538-2546.
  64. Hensley, K., Kotake, Y., Sang, H., Pye, Q. N., Wallis, G. L., Kolker, L. M., Tabatabaie, T., Stewart, C. A., Konishi, Y., Nakae, D., and Floyd, R. A. (2000) Dietary choline restriction causes complex I dysfunction and increased H2O2 generation in liver mitochondria. Carcinogenesis 21:983-989.
  65. Overkamp, K. M., Bakker, B. M., Kotter, P., van Tuijl, A., de Vries, S., Van Dijken, J. P., and Pronk, J. T. (2000) In vivo analysis of the mechanisms for oxidation of cytosolic NADH by Saccharomyces cerevisiae mitochondria . J. Bacteriol. 182:2823-2830.
  66. Schägger, H. and Pfeiffer, K. (2000) Supercomplexes in the respiratory chains of yeast and mammalian mitochondria . EMBO J. 19:1777-1783.
  67. Bradley, J. L., Blake, J. C., Chamberlain, S., Thomas, P. K., Cooper, J. M., and Schapira, A. H. (2000) Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia. Hum. Mol. Genet. 9:275-282.
  68. Bjorklof, K., Zickermann, V., and Finel, M. (2000) Purification of the 45 kDa, membrane bound NADH dehydrogenase of Escherichia coli (NDH-2) and analysis of its interaction with ubiquinone analogues. FEBS Lett. 467:105-110.
  69. Oliveira, P. J., Santos, D. J., and Moreno, A. J. (2000) Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria. Arch. Biochem. Biophys. 374:279-285.
  70. Kim, C. G., Zhou, H. Z., Imura, Y., Tominaga, O., Su, Z. H., and Osawa, S. (2000) Pattern of morphological diversification in the Leptocarabus ground beetles (Coleoptera: Carabidae) as deduced from mitochondrial ND5 gene and nuclear 28S rDNA sequences. Mol. Biol. Evol. 17:137-145.
  71. Vielhaber, S., Feistner, H., Schneider, W., Weis, J., and Kunz, W. S. (2000) Mitochondrial complex I deficiency in a female with multiplex arthrogryposis congenita. Pediatr. Neurol. 22:53-56.
  72. Simon, D. K., Mayeux, R., Marder, K., Kowall, N. W., Beal, M. F., and Johns, D. R. (2000) Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease. Neurology 54 :703-709.
  73. Fisher, N. and Rich, P. R. (2000) A motif for quinone binding sites in respiratory and photosynthetic systems. J. Mol. Biol. 296:1153-1162.
  74. Plesofsky, N., Gardner, N., Videira, A., and Brambl, R. (2000) NADH dehydrogenase in Neurospora crassa contains myristic acid covalently linked to the ND5 subunit peptide. Biochim. Biophys. Acta 1495:223-230.
  75. Brooks, H. and Krahenbuhl, S. (2000) Development of a new assay for complex I of the respiratory chain. Clin. Chem. 46:345-350.
  76. Scacco, S., Vergari, R., Scarpulla, R. C., Technikova-Dobrova, Z., Sardanelli, A., Lambo, R., Lorusso, V., and Papa, S. (2000) cAMP-dependent phosphorylation of the nuclear-encoded 18kDA(IP) subunit of respiratory complex I and activation of the complex in serum-starved mouse fibroblast cultures. J. Biol. Chem. 275:17578-17582.
  77. Guera, A., de Nova, P. G., and Sabater, B. (2000) Identification of the Ndh (NAD(P)H-plastoquinone-oxidoreductase) complex in etioplast membranes of barley: changes during photomorphogenesis of chloroplasts . Plant Cell Physiol 41:49-59.
  78. Baumer, S., Ide, T., Jacobi, C., Johann, A., Gottschalk, G., and Deppenmeier, U. (2000) The F420H2 Dehydrogenase from Methanosarcina mazei is a Redox-driven Proton Pump Closely Related to NADH Dehydrogenases. J. Biol. Chem. 275:17968-17973.
  79. Enriquez, J. A., Cabezas-Herrera, J., Bayona-Bafaluy, M. P., and Attardi, G. (2000) Very Rare Complementation between Mitochondria Carrying Different Mitochondrial DNA Mutations Points to Intrinsic Genetic Autonomy of the Organelles in Cultured Human Cells. J. Biol. Chem. 275: 11207-11215.
  80. Brangeon, J., Sabar, M., Gutierres, S., Combettes, B., Bove, J., Gendy, C., Chetrit, P., Des Francs-Small, C. C., Pla, M., Vedel, F., and De Paepe, R. (2000) Defective splicing of the first nad4 intron is associated with lack of several complex I subunits in the nicotiana sylvestris NMS1 nuclear mutant . Plant J. 21:269-280.
  81. Steuber, J., Schmid, C., Rufibach, M., and Dimroth, P. (2000) Na+ translocation by complex I (NADH:quinone oxidoreductase) of Escherichia coli. Mol. Microbiol. 35:428-434.
  82. Claas, K., Weber, S., and Downs, D. M. (2000) Lesions in the nuo operon, encoding NADH dehydrogenase complex I, prevent PurF-independent thiamine synthesis and reduce flux through the oxidative pentose phosphate pathway in salmonella enterica serovar typhimurium.  J. Bacteriol. 182:228-232.
  83. Loeffen, J. L., Smeitink, J. A., Trijbels, J. M., Janssen, A. J., Triepels, R. H., Sengers, R. C., and Van den Heuvel, L. P. (2000) Isolated complex I deficiency in children: Clinical, biochemical and genetic aspects. Hum. Mutat. 15:123-134.
  84. Bai, Y., Shakeley, R. M., and Attardi, G. (2000) Tight control of respiration by NADH dehydrogenase ND5 subunit gene expression in mouse mitochondria. Mol. Cell Biol. 20:805-815.
  85. Casano, L. M., Zapata, J. M., Martin, M., and Sabater, B. (2000) Chlororespiration and poising of cyclic electron transport. Plastoquinone As electron transporter between thylakoid nadh dehydrogenase and peroxidase. J. Biol. Chem. 275:942-948.
  86. Enns, G. M., Bennett, M. J., Hoppel, C. L., Goodman, S. I., Weisiger, K., Ohnstad, C., Golabi, M., and Packman, S. (2000) Mitochondrial respiratory chain complex I deficiency with clinical and biochemical features of long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency. J. Pediatr. 136:251-254.
  87. Yamaguchi, M., Belogrudov, G. I.,  Matsuno-Yagi, A., and Hatefi, Y. (2000) The multiple nicotinamide nucleotide-binding subunits of bovine heart mitochondrial NADH:ubiquinone oxidoreductase (complex I). Eur.J.Biochem.267:329-336.
  88. El-Mir, M.-Y., Nogueira, V., Fontaine, E., Avéret, N., Rigoulet, M., and Leverve, X. (2000) Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J.Biol.Chem. 275:223-228.

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