Properties of Iron-Sulfur Clusters of Complex I/NDH-1
| Center |
Cluster |
Subunit |
Complex I
|
Bacterial NDH-1
|
FeS Binding motifs |
| Em (mV) |
pH dep |
Em (mV) |
pH dep |
| N1a |
[2Fe-2S] |
FP24K/Nqo2/NuoE |
-370 |
+ |
(-150?) |
+ |
CxxxxCx35CxxxC |
| N1b |
[2Fe-2S] |
IP75K/Nqo3/NuoG |
-250 |
- |
-260 |
- |
Cx10CxxCx13C |
| N2 |
[4Fe-4S] |
PSST/Nqo6/NuoB(?) |
-50~-150 |
+ |
-130 |
+ |
CCx63Cx29CP |
| N3 |
[4Fe-4S] |
FP51K/Nqo1/NuoF |
-250 |
- |
-240 |
- |
CxxCxxCx39C |
| N4 |
[4Fe-4S] |
IP75K/Nqo3/NuoG |
-250 |
- |
-270 |
- |
CxxCxxCx42-43C |
| N5 |
[4Fe-4S] |
IP75K/Nqo3/NuoG |
-250 |
- |
|
? |
HxxxCxxCxxxxxC |
| N6 |
2[4Fe-4S] |
TYKY/Nqo9/NuoI |
|
? |
|
? |
(CxxCxxCxxxCP)2 |
| N7 |
[4Fe-4S] |
IP75K/Nqo3/NuoG |
|
? |
|
? |
CxxCxxxCx27C |